Evidence map›Paper›PMID 36232996›Full record

ArticleInternational journal of molecular sciences2022

Anastasiya A Kobelyatskaya, Alexander A Kudryavtsev, Anna V Kudryavtseva, Anastasiya V Snezhkina, Maria S Fedorova, Dmitry V Kalinin, Vladislav S Pavlov, Zulfiya G Guvatova, Pavel A Naberezhnev, Kirill M Nyushko and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. AI-Driven Prediction of Cardio-Oncology Biomarkers Through Protein Corona Analysis.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Anastasiya A KobelyatskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Alexander A KudryavtsevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Anna V KudryavtsevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-3722-8207
Anastasiya V SnezhkinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-4421-4364
Maria S FedorovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6893-4673
Dmitry V KalininVishnevsky Institute of Surgery, Ministry of Health of the Russian Federation, 117997 Moscow, Russia.
Vladislav S PavlovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-2942-6393
Zulfiya G GuvatovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0003-3494-9807
Pavel A NaberezhnevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Kirill M NyushkoNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, 125284 Moscow, Russia.
Boris Y AlekseevNational Medical Research Radiological Center, Ministry of Health of the Russian Federation, 125284 Moscow, Russia.
George S KrasnovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-6493-8378
Elizaveta V BulavkinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Elena A PudovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Engelhardt Institute of Molecular Biology · RUMinistry of Health of the Russian Federation · RU

Funding

Russian Science Foundation 18-75-10127
6 · The paper itself

Abstract

Following radical surgery, patients may suffer a relapse. It is important to identify such patients so that therapy tactics can be modified appropriately. Existing stratification schemes do not display the probability of recurrence with enough precision since locally advanced prostate cancer (PCa) is classified as high-risk but is not ranked in greater detail. Between 40 and 50% of PCa cases belong to the TMPRSS2-ERG subtype that is a sufficiently homogeneous group for high-precision prognostic marker search to be possible. This study includes two independent cohorts and is based on high throughput sequencing and qPCR data. As a result, we have been able to suggest a perspective-trained model involving a deep neural network based on both qPCR data for mRNA and miRNA and clinicopathological criteria that can be used for recurrence risk forecasts in patients with TMPRSS2-ERG-positive, locally advanced PCa (the model uses

Indexed as

MicroRNAsProstatic NeoplasmsHeat-Shock ProteinsHumansMaleNeoplasm Recurrence, LocalOncogene Proteins, FusionOxidoreductases Acting on Sulfur Group DonorsRNA, MessengerSerine EndopeptidasesTranscriptional Regulator ERGERG protein, humanHeat-Shock ProteinsMicroRNAsMIRN503 microRNA, humanODF2 protein, humanOncogene Proteins, FusionOxidoreductases Acting on Sulfur Group DonorsQSOX2 protein, humanRNA, MessengerSerine EndopeptidasesTMPRSS2-ERG fusion protein, humanTMPRSS2 protein, humanTranscriptional Regulator ERGexpressionforecastingmiRNA-Seqneural networkprimary tumorprostate cancerrecurrenceRNA-SeqsubtypeTMPRSS2-ERG

Identifiers

PMID36232996
PMCPMC9569942
OpenAlexW4303699481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.