Evidence map›Paper›PMID 36232961›Full record

ArticleInternational journal of molecular sciences2022

Relative Abundance of Lipid Metabolites in Spermatozoa across Three Compartments.

Samuel Furse, Laura C Kusinski, Alison Ray, Coralie Glenn-Sansum, Huw E L Williams, Albert Koulman, Claire L Meek

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Age-Associated Metabolomic Changes in Human Spermatozoa.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Quantitative Analysis of the Human Semen Phosphorometabolome byInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Review
  15. Sterol and lipid metabolism in bees.Metabolomics : Official journal of the Metabolomic Society · 2023
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Samuel FurseWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.ORCID 0000-0003-4267-2051
Laura C KusinskiWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
Alison RayDepartment of Clinical Chemistry and Immunology, Peterborough City Hospital, North West Anglia NHS Foundation Trust, Bretton Gate, Peterborough PE3 9GZ, UK.
Coralie Glenn-SansumR&D Department, Peterborough City Hospital, North West Anglia NHS Foundation Trust, Bretton Gate, Peterborough PE3 9GZ, UK.
Huw E L WilliamsCentre for Biomolecular Sciences, School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Albert KoulmanWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.ORCID 0000-0001-9998-051X
Claire L MeekWellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Box 289, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
University of Cambridge · GBPeterborough City Hospital · GBUniversity of Nottingham · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M027252/1Diabetes UK 17/0005712EFSD - Novo Nordisk Foundation NNF19SA058974
6 · The paper itself

Abstract

Male fertility, as manifest by the quantity and progressive motility of spermatozoa, is negatively impacted by obesity, dyslipidaemia and metabolic disease. However, the relative distribution of lipids in spermatozoa and the two compartments which supply lipids for spermatogenesis (seminal fluid and blood serum) has not been studied. We hypothesised that altered availability of lipids in blood serum and seminal fluid may affect the lipid composition and progressive motility of sperm. 60 men of age 35 years (median (range 20-45) and BMI 30.4 kg/m

Indexed as

SemenSperm MotilityAdultCeramidesCholesterolFatty AcidsHumansMaleMiddle AgedPhosphatidylcholinesPhosphatidylethanolaminesPlasmalogensSpermatozoaSperm CountSphingomyelinsTriglyceridesCeramidesCholesterolFatty AcidsPhosphatidylcholinesPhosphatidylethanolaminesPlasmalogensSphingomyelinsTriglyceridesfertilitylipid dysfunctionlipidomicsmale infertilitymetabolismprogressive motilityspermatozoa

Identifiers

PMID36232961
PMCPMC9569887
OpenAlexW4303699536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.