Evidence map›Paper›PMID 36232957›Full record

ReviewInternational journal of molecular sciences2022

Novel Biomarkers and Therapeutic Targets for Melanoma.

Noa Sabag, Alexander Yakobson, Meir Retchkiman, Eldad Silberstein

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Sphingolipid metabolism and regulated cell death in malignant melanoma.Apoptosis : an international journal on programmed cell death · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Noa SabagDepartment of Plastic Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer Sheva 8410100, Israel.
Alexander YakobsonOncology Institute, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 151, Beer Sheva 84100, Israel.
Meir RetchkimanDepartment of Plastic Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer Sheva 8410100, Israel.
Eldad SilbersteinDepartment of Plastic Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer Sheva 8410100, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant melanoma is one of the most common cancers in the world. In the disease's early stages, treatment involves surgery, in advanced stages however, treatment options were once scarce. There has been a paradigm shift in advanced melanoma treatment with the introduction of immunotherapy and targeted therapies. Understanding the molecular pathways and their pathologic counterparts helped identifying specific biomarkers that lead to the development of specific targeted therapies. In this review we briefly present some of these markers and their relevance to melanoma treatment.

Indexed as

MelanomaSkin NeoplasmsBiomarkersHumansImmunotherapyMolecular Targeted TherapyBiomarkersadjuvant therapyimmunotherapymalignant melanomatargeted therapy

Identifiers

PMID36232957
PMCPMC9570448

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.