Evidence map›Paper›PMID 36232954›Full record

ArticleInternational journal of molecular sciences2022

Anticancer Properties of

Przemysław Sitarek, Ewelina Synowiec, Tomasz Kowalczyk, Gabrielle Bangay, Tomasz Śliwiński, Laurent Picot, Salvatore Princiotto, Patricia Rijo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Bioactive Compounds ofMolecules (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Plants (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Biological Properties of Extracts Obtained from In Vitro Culture ofInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Mechanisms of Phytochemicals in Anti-Inflammatory and Anti-Cancer.International journal of molecular sciences · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Przemysław SitarekDepartment of Biology and Pharmaceutical Botany, Medical University of Lodz, ul. Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0001-5495-3550
Ewelina SynowiecLaboratory of Medical Genetics, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Tomasz KowalczykDepartment of Molecular Biotechnology and Genetics, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-4559-5015
Gabrielle BangayCBIOS-Universidade Lusófona's Research Center for Biosciences and Health Technologies, 1749-024 Lisbon, Portugal.ORCID 0000-0003-2545-1812
Tomasz ŚliwińskiLaboratory of Medical Genetics, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0001-8385-7744
Laurent PicotLittoral Environnement et Sociétés UMRi CNRS 7266 LIENSs, La Rochelle Université, 17042 La Rochelle, France.ORCID 0000-0003-4656-3557
Salvatore PrinciottoCBIOS-Universidade Lusófona's Research Center for Biosciences and Health Technologies, 1749-024 Lisbon, Portugal.ORCID 0000-0003-3440-8373
Patricia RijoDepartment of Molecular Biotechnology and Genetics, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0001-7992-8343
University of Łódź · PLUniversidade Lusófona · PTCentre National de la Recherche Scientifique · FRMedical University of Lodz · PLUniversity of Lisbon · PT

Funding

Fundação para a Ciência e Tecnologia projects UIDB/04567/2020 and UIDP/04567/2020 Ph.D. grant (UI/BD/151422/2021
6 · The paper itself

Abstract

Since cancer treatment by radio- and chemotherapy has been linked to safety concerns, there is a need for new and alternative anticancer drugs; as such, compounds isolated from plants represent promising candidates. The current study investigates the anticancer features of halimane (11R*,13E)-11-acetoxyhalima-5,13-dien-15-oic acid (HAL) and the labdane diterpenes 1α,6β-diacetoxy-8α,13

Indexed as

Antineoplastic AgentsDiterpenesPlectranthusApoptosisbcl-2-Associated X ProteinCaspase 3Cell Line, TumorColforsinDNA, MitochondrialFluorescent DyesIodidesMembrane Potential, MitochondrialMyeloid Cell Leukemia Sequence 1 ProteinPhytochemicalsProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesAntineoplastic Agentsbcl-2-Associated X ProteinCaspase 3ColforsinDiterpenesDNA, MitochondrialFluorescent DyesIodidesMyeloid Cell Leukemia Sequence 1 ProteinPhytochemicalsProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesSuperoxidesanticancer effectapoptosis inductionditerpenesmitochondrial pathwayPlectranthus ornatus

Identifiers

PMID36232954
PMCPMC9569850
OpenAlexW4303699551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.