ArticleInternational journal of molecular sciences2022
The Changes in Canine Parvovirus Variants over the Years.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Expanded detection of canine enteric viruses in UK dogs with diarrhoea.Microbial genomics · 2026Article
- Impact of VP2 mutations on viral fitness in canine parvovirus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Article
- Histopathological Myocardial Changes and CPV-2 DNA Detection in Young Dogs: A Retrospective Study.Veterinary sciences · 2026Article
- Development of canine parvovirus-2-based recombinant pseudoviruses expression system: a potential vaccine platform.Veterinary research · 2026Article
- Seroprevalence and associated risk factors for feline panleukopenia virus infection among managed giant pandas in China.Veterinary research · 2026Article
- Development and Validation of a Recombinant VP2-Based Indirect ELISA for Canine Parvovirus.Microorganisms · 2026Article
- Molecular Characteristics and Genetic Diversity of Canine Parvovirus in Shanghai, China, from 2016 to 2025.Microorganisms · 2026Article
- Canine parvovirus type 2 infection in vaccinated puppies: role of vaccination practices and viral antigenic variation.BMC veterinary research · 2026Article
- Molecular characterisation of viral pathogens associated with respiratory and gastrointestinal infections in dogs in Türkiye - preliminary study.Journal of veterinary research · 2026Article
- Genomic Characterization of Clinical Canine Parvovirus Type 2c Infection in Wild Coyotes (Pathogens (Basel, Switzerland) · 2026Article
- Feline panleukopenia virus and canine parvovirus: development of two qPCR assays with high-resolution melting analysis and molecular epidemiology in dogs and cats from Northen Italy in 2017-2023.Frontiers in veterinary science · 2026Article
- Parvoviruses at the Heart: Endothelial Injury and Myocyte Lysis in Human B19V and Canine CPV-2 Infections.Current issues in molecular biology · 2025Review
- Deferoxamine Inhibits Canine Parvovirus by Suppressing Ferroptosis and Viral Replication.Veterinary sciences · 2025Article
- Canine Cardiac and Cardiovascular Pathology: Four Major Life-Threatening Non-Degenerative, Non-Hereditary Conditions.Veterinary sciences · 2025Review
- Isolation, Identification and Phylogenetic Analysis of Canine Parvovirus Type 2c in Two Regions of Iran.Veterinary medicine and science · 2025Article
- Virome of canine lymph nodes: identification of viruses with zoonotic potential.Virology journal · 2025Article
- Residues 27T and 297A in VP2 contribute to the enhanced replication and pathogenicity of raccoon dog parvovirus.Journal of virology · 2025Article
- Isolation and genetic characterization of parvovirus from Bengal tiger in China.Virology journal · 2025Article
- Cross-species characterization of feline parvovirus and Feline-Origin canine parvovirus Southern China (2023-2024): insights into epidemiology, genetic evolution and recombination.BMC veterinary research · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Canine parvovirus (CPV-2) is one of the most important pathogens in dogs, and despite the continual development of vaccines against CPV-2, CPV-2 is still circulating in the canine population. The CPV-2a/2b/2c variant has replaced the original CPV-2 virus and seems to exhibit accelerated transmission. Although CPV-2 infection has been frequently reported, no studies have summarized information of CPV-2 variants currently circulating worldwide. To track the evolution of CPV-2, we downloaded and analyzed all VP2 sequences from the NCBI database (from 1978 to 2022). We found that CPV-2c shows a tendency to replace CPV-2a as the new dominant variant in Asia, South America, North America and Africa. Additionally, CPV-2c, which is prevalent in most regions of Asia, carries two special mutations in VP2, A5G and Q370R, and has become a dominant mutation with spillover already occurring. In conclusion, this summary of the types of global epidemic variants provides new insight into the evolution of CPV-2 and raises awareness for blocking the spread of this virus. The spread of Asian-derived CPV-2c urgently needs to be further under surveillance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.