Evidence map›Paper›PMID 36232815›Full record

ArticleInternational journal of molecular sciences2022

Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis.

Peter P Issa, Mahmoud Omar, Chad P Issa, Yusef Buti, Mohammad Hussein, Mohamed Aboueisha, Ali Abdelhady, Mohamed Shama, Grace S Lee, Eman Toraih and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter P IssaSchool of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-5248-3142
Mahmoud OmarDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Chad P IssaSchool of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Yusef ButiDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Mohammad HusseinDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Mohamed AboueishaDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Ali AbdelhadyDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Mohamed ShamaDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Grace S LeeDepartment of Surgery, School of Medicine, Yale University, New Haven, CT 06520, USA.ORCID 0000-0001-7648-4150
Eman ToraihDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.ORCID 0000-0001-9267-3787
Emad KandilDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
American Thyroid Association THYROIDGRANT2021-0000000232NCATS NIH HHS UL1 TR001863Tulane University Bridge Fund
6 · The paper itself

Abstract

Thyroid nodules can be classified as benign, malignant, or indeterminate, the latter of which make up 10-30% of nodules. Radiofrequency ablation (RFA) has become an attractive and promising therapy for the treatment of benign thyroid nodules. However, few studies have investigated the safety and efficacy of RFA for the management of indeterminate thyroid nodules. In this study, 178 patients with thyroid nodules diagnosed as benign (Bethesda II) or indeterminate (Bethesda III/IV) by preoperative cytopathological analysis were included. Patients in the benign and indeterminate cohorts had similar thyroid nodule volume reduction rates at 65.60% and 64.20%, respectively (

Indexed as

Catheter AblationRadiofrequency AblationThyroid NoduleHumansNorth AmericaRetrospective StudiesTreatment OutcomeBethesda IIIBethesda IVindeterminate thyroid nodulesradiofrequency ablationRFAthyroid

Identifiers

PMID36232815
PMCPMC9569520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.