Evidence map›Paper›PMID 36232792›Full record

ReviewInternational journal of molecular sciences2022

A Survey on Computational Methods for Investigation on ncRNA-Disease Association through the Mode of Action Perspective.

Dongmin Bang, Jeonghyeon Gu, Joonhyeong Park, Dabin Jeong, Bonil Koo, Jungseob Yi, Jihye Shin, Inuk Jung, Sun Kim, Sunho Lee

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Non-coding RNA-mediated gene regulation in Alzheimer's disease pathogenesis: molecular insights and emerging innovations.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Review
  3. Article
  4. miRNAs in Heart Development and Disease.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dongmin BangInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-9217-8380
Jeonghyeon GuInterdisciplinary Program in Artificial Intelligence, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-7136-204X
Joonhyeong ParkDepartment of Computer Science and Engineering, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-4477-1651
Dabin JeongInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-9910-8051
Bonil KooInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-4357-1850
Jungseob YiInterdisciplinary Program in Artificial Intelligence, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-5127-7224
Jihye ShinInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-8593-0607
Inuk JungDepartment of Computer Science and Engineering, Kyungpook National University, Daegu 41566, Korea.ORCID 0000-0003-0675-4244
Sun KimInterdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-5385-9546
Sunho LeeAIGENDRUG Co., Ltd., Seoul 08826, Korea.ORCID 0000-0001-9534-3337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular and sequencing technologies have been successfully used in decoding biological mechanisms of various diseases. As revealed by many novel discoveries, the role of non-coding RNAs (ncRNAs) in understanding disease mechanisms is becoming increasingly important. Since ncRNAs primarily act as regulators of transcription, associating ncRNAs with diseases involves multiple inference steps. Leveraging the fast-accumulating high-throughput screening results, a number of computational models predicting ncRNA-disease associations have been developed. These tools suggest novel disease-related biomarkers or therapeutic targetable ncRNAs, contributing to the realization of precision medicine. In this survey, we first introduce the biological roles of different ncRNAs and summarize the databases containing ncRNA-disease associations. Then, we suggest a new trend in recent computational prediction of ncRNA-disease association, which is the

Indexed as

Computational BiologyRNA, UntranslatedBiomarkersRNA, MessengerBiomarkersRNA, MessengerRNA, Untranslateddeep learningdisease associationintegrative analysismode of actionnetwork miningnon-coding RNA

Identifiers

PMID36232792
PMCPMC9570358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.