Evidence map›Paper›PMID 36232790›Full record

ArticleInternational journal of molecular sciences2022

Two Cases of Autoimmune Thyroid Disorders after COVID Vaccination in Dialysis Patients.

Georgios Lioulios, Ioannis Tsouchnikas, Chrysostomos Dimitriadis, Panagiotis Giamalis, Eva Pella, Michalis Christodoulou, Maria Stangou, Aikaterini Papagianni

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Chronic inflammatory demyelinating polyneuropathy in end-stage renal disease patients: a case series study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Georgios LiouliosDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.
Ioannis TsouchnikasDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.
Chrysostomos DimitriadisDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.
Panagiotis GiamalisDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.
Eva PellaDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.ORCID 0000-0001-8383-2184
Michalis ChristodoulouDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.ORCID 0000-0001-9565-6931
Maria StangouDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.ORCID 0000-0003-2496-9863
Aikaterini PapagianniDepartment of Nephrology, School of Medicine, Aristotle University of Thessaloniki, General Hospital "Hippokratio", 54642 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 infection and vaccination have been associated with autoimmune thyroid dysfunctions. Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) and molecular mimicry have been referred to as potential causes. Such a case has not been reported in immunocompromised end-stage renal disease (ESRD) patients. Herein we present two dialysis patients with no previous history of thyroid disease who developed immune mediated thyroid disorders after BNT162b mRNA vaccine against SARS-CoV-2. The first patient is a 29-year-old man on hemodialysis diagnosed with Grave's disease four months post-vaccination and the second one is a 67-year-old female on peritoneal dialysis who developed Hashimoto's thyroiditis two months post-vaccination. Grave's disease is uncommon in dialysis patients, whereas Hashimoto's thyroiditis has a higher incidence in this population. Time proximity in both cases suggests potential causality. To our knowledge, this is the first report of de novo immune-mediated thyroid disorders in dialysis patients following vaccination against SARS-CoV-2.

Indexed as

COVID-19COVID-19 VaccinesGraves DiseaseHashimoto DiseaseAdultAgedFemaleHumansMalemRNA VaccinesRenal DialysisSARS-CoV-2VaccinationVaccines, SyntheticCOVID-19 VaccinesmRNA VaccinesVaccines, SyntheticBNT162b2ESRDGrave’s diseaseHashimoto’s diseasehemodialysisperitoneal dialysisSARS-CoV-2vaccination

Identifiers

PMID36232790
PMCPMC9570111
OpenAlexW4297977827

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.