Evidence map›Paper›PMID 36232774›Full record

ArticleInternational journal of molecular sciences2022

Mengping Long, Chong You, Qianqian Song, Lina X J Hu, Zhaorong Guo, Qian Yao, Wei Hou, Wei Sun, Baosheng Liang, Xiaohua Zhou and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Mengping LongDepartment of Pathology, Peking University Cancer Hospital, Beijing 100083, China.
Chong YouChongqing Research Institute of Big Data, Peking University, Chongqing 401121, China.
Qianqian SongDepartment of Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Lina X J HuDepartment of Pathology, Alaska Native Medical Center, Anchorage, AK 99501, USA.
Zhaorong GuoDepartment of Breast Center, Peking University Cancer Hospital, Beijing 100083, China.
Qian YaoDepartment of Pathology, Peking University Cancer Hospital, Beijing 100083, China.
Wei HouDepartment of Pathology, Peking University Cancer Hospital, Beijing 100083, China.
Wei SunDepartment of Pathology, Peking University Cancer Hospital, Beijing 100083, China.
Baosheng LiangDepartment of Biostatistics, School of Public Health, Peking University, Beijing 100191, China.ORCID 0000-0003-3500-0820
Xiaohua ZhouChongqing Research Institute of Big Data, Peking University, Chongqing 401121, China.
Yiqiang LiuDepartment of Pathology, Peking University Cancer Hospital, Beijing 100083, China.ORCID 0000-0002-7239-2360
Taobo HuChongqing Research Institute of Big Data, Peking University, Chongqing 401121, China.ORCID 0000-0001-5124-7167
Peking University · CNAlaska Native Medical Center · US

Funding

National Natural Science Foundation of China 82002979Research and Development Funds of Peking University People's Hospital RDX2021-05Research and Development Funds of Peking University People's Hospital RDY2020-16Young Investigator Program of Peking University Health Science Center BMU2021PYB013
6 · The paper itself

Abstract

Androgen receptor (AR) expression is frequently observed in breast cancer, but its association with estrogen receptor (ER) expression in breast cancer remains unclear. This study analyzed the clinicopathological and molecular features associated with AR negativity in both ER-positive and ER-negative breast cancer, trying to elucidate the molecular correlation between AR and ER. Our results showed that AR negativity was associated with different clinicopathological characteristics and molecular features in ER-positive and ER-negative breast cancer. Moreover, AR-positive breast cancer has better clinicopathological features than AR-negative breast cancer, especially in the ER-negative subtype. These results suggest that the role of AR in ER-negative breast cancer is distinctive from that in ER-positive breast cancer.

Indexed as

Breast NeoplasmsReceptors, AndrogenAndrogensFemaleGenomicsHumansReceptors, EstrogenAndrogensReceptors, AndrogenReceptors, Estrogenandrogen receptorbreast cancerestrogen receptormolecular feature

Identifiers

PMID36232774
PMCPMC9570294
OpenAlexW4298002935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.