ArticleInternational journal of molecular sciences2022
Preparation of Highly Crystalline Silk Nanofibrils and Their Use in the Improvement of the Mechanical Properties of Silk Films.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- One-Step Preparation of Silk Fibroin and Sericin from Silkworm Cocoons Using High-Temperature High-Pressure Treatment.Polymers · 2026Article
- A Simplified Method for the Preparation of Highly Conductive and Flexible Silk Nanofibrils/MXene Membrane.Materials (Basel, Switzerland) · 2023Article
- Structural Characteristics and Properties of Cocoon and Regenerated Silk Fibroin from Different Silkworm Strains.International journal of molecular sciences · 2023Article
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Authors and funding
3 authors.
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Abstract
Due to their commendable biocompatibility, regenerated silk fibroin (RSF) films have attracted considerable research interest. However, the poor mechanical properties of RSF films have limited their use in various biomedical applications. In this study, a novel, highly crystalline silk fibril was successfully extracted from silk by combining degumming with ultrasonication. Ultrasonication accelerated the development of silk nanofibrils measuring 130-200 nm on the surface of the over-degummed silk fibers, which was confirmed via scanning electron microscopy. Additionally, the crystallinity index of silk fibril was found to be significantly higher (~68%) than that of conventionally degummed silk (~54%), as confirmed by the Fourier-transform infrared (FTIR) spectroscopy results. Furthermore, the breaking strength and elongation of the RSF film were increased 1.6 fold and 3.4 fold, respectively, following the addition of 15% silk nanofibrils. Thus, the mechanical properties of the RSF film were remarkably improved by the addition of the silk nanofibrils, implying that it can be used as an excellent reinforcing material for RSF films.
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