Evidence map›Paper›PMID 36232631›Full record

ArticleInternational journal of molecular sciences2022

Efficacy and Renal Safety of Prophylactic Tenofovir Alafenamide for HBV-Infected Cancer Patients Undergoing Chemotherapy.

I-Cheng Lee, Keng-Hsin Lan, Chien-Wei Su, Chung-Pin Li, Yee Chao, Han-Chieh Lin, Ming-Chih Hou, Yi-Hsiang Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

I-Cheng LeeDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-9316-4682
Keng-Hsin LanDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chien-Wei SuDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-3889-7004
Chung-Pin LiDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-2123-8264
Yee ChaoCancer Center, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0001-5578-340X
Han-Chieh LinDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Ming-Chih HouDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yi-Hsiang HuangDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0001-5241-5425
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST 109-2628-B-075-022, MOST 109-2314-B-010-034-MY3, MOST 110-2314-B-075-052, MOST 111-2314-B-075-055Taipei Veterans General Hospital, Taipei, Taiwan V110C-094, V110C-144, V111C-114, V111C-107
6 · The paper itself

Abstract

There are no data comparing the efficacy and safety of prophylactic entecavir (ETV), tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) for HBV-infected cancer patients undergoing chemotherapy. This study aimed to compare the efficacy and renal safety of ETV, TDF and TAF in this setting. HBsAg-positive cancer patients treated with ETV (n = 582), TDF (n = 200) and TAF (n = 188) during chemotherapy were retrospectively enrolled. Antiviral efficacy and risk of renal events were evaluated. The rate of complete viral suppression at 1 year was 94.7%, 94.7% and 96.1% in ETV, TDF and TAF groups, respectively (

Indexed as

Acute Kidney InjuryNeoplasmsAdenineAlanineAntiviral AgentsCisplatinHepatitis B Surface AntigensHepatitis B virusHumansKidneyRetrospective StudiesTenofovirTreatment OutcomeAdenineAlanineAntiviral AgentsCisplatinHepatitis B Surface AntigensTenofovirtenofovir alafenamidecancerchemotherapyentecavirhepatitis B virustenofovir alafenamidetenofovir disoproxil fumarate

Identifiers

PMID36232631
PMCPMC9569539
OpenAlexW4297539448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.