Evidence map›Paper›PMID 36232571›Full record

ReviewInternational journal of molecular sciences2022

Precision Medicine Approaches with Metabolomics and Artificial Intelligence.

Elettra Barberis, Shahzaib Khoso, Antonio Sica, Marco Falasca, Alessandra Gennari, Francesco Dondero, Antreas Afantitis, Marcello Manfredi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  15. A Pilot Metabolomic Study for DiagnosingInternational journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elettra BarberisDepartment of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Shahzaib KhosoDepartment of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Antonio SicaDepartment of Pharmaceutical Sciences, University of Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0002-8342-7442
Marco FalascaMetabolic Signaling Group, Curtin Medical School, Curtin University, Perth 6845, Australia.ORCID 0000-0002-9801-7235
Alessandra GennariDepartment of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Francesco DonderoDepartment of Sciences and Technological Innovation, University of Piemonte Orientale, 15100 Alessandria, Italy.ORCID 0000-0001-7945-3712
Antreas AfantitisNovaMechanics Ltd., Digeni Akrita 51, Nicosia 1070, Cyprus.ORCID 0000-0002-0977-8180
Marcello ManfrediDepartment of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy.

Funding

MIUR Italy Department of Excellence
6 · The paper itself

Abstract

Recent technological innovations in the field of mass spectrometry have supported the use of metabolomics analysis for precision medicine. This growth has been allowed also by the application of algorithms to data analysis, including multivariate and machine learning methods, which are fundamental to managing large number of variables and samples. In the present review, we reported and discussed the application of artificial intelligence (AI) strategies for metabolomics data analysis. Particularly, we focused on widely used non-linear machine learning classifiers, such as ANN, random forest, and support vector machine (SVM) algorithms. A discussion of recent studies and research focused on disease classification, biomarker identification and early diagnosis is presented. Challenges in the implementation of metabolomics-AI systems, limitations thereof and recent tools were also discussed.

Indexed as

Artificial IntelligencePrecision MedicineAlgorithmsMachine LearningSupport Vector Machineartificial intelligencebiomarkersmachine learningmetabolomicsprecision medicine

Identifiers

PMID36232571
PMCPMC9569627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.