Evidence map›Paper›PMID 36232561›Full record

ReviewInternational journal of molecular sciences2022

Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy.

Buhle Buyana, Tobeka Naki, Sibusiso Alven, Blessing Atim Aderibigbe

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Buhle BuyanaDepartment of Chemistry, University of Fort Hare, Alice 5700, Eastern Cape Province, South Africa.
Tobeka NakiDepartment of Chemistry, University of Fort Hare, Alice 5700, Eastern Cape Province, South Africa.
Sibusiso AlvenDepartment of Chemistry, University of Fort Hare, Alice 5700, Eastern Cape Province, South Africa.ORCID 0000-0001-7100-4007
Blessing Atim AderibigbeDepartment of Chemistry, University of Fort Hare, Alice 5700, Eastern Cape Province, South Africa.
University of Fort Hare · ZA

Funding

South African Medical Research Council SAMRC
6 · The paper itself

Abstract

Colorectal cancer is a common cancer in both men and women. Numerous studies on the therapeutic effectiveness of nanoparticles against colorectal cancer have been reported. Platinum treatments as well as other medications comprising of nanoparticles have been utilized. Drug resistance restricts the use of platinum medicines, despite their considerable efficacy against a variety of cancers. This review reports clinically licensed platinum medicines (cisplatin, carboplatin, and oxaliplatin) combined with various nanoparticles that have been evaluated for their therapeutic efficacy in the treatment of colorectal cancer, including their mechanism of action, resistance, and limitations.

Indexed as

Antineoplastic AgentsColorectal NeoplasmsNanoparticlesCarboplatinCisplatinFemaleHumansMaleOrganoplatinum CompoundsOxaliplatinPlatinumAntineoplastic AgentsCarboplatinCisplatinOrganoplatinum CompoundsOxaliplatinPlatinumanticancer drugscoloncolorectal cancernanoparticlesplatinumrectum

Identifiers

PMID36232561
PMCPMC9569963
OpenAlexW4297235630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.