Evidence map›Paper›PMID 36232546›Full record

ReviewInternational journal of molecular sciences2022

Anna A Ogienko, Evgeniya S Omelina, Oleg V Bylino, Mikhail A Batin, Pavel G Georgiev, Alexey V Pindyurin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Distribution Analysis of the Lifespan Trait in Drosophila.International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. NF-κB-mediated developmental delay extends lifespan inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. IntegratingFrontiers in pharmacology · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna A OgienkoDepartment of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0002-0896-1899
Evgeniya S OmelinaDepartment of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology SB RAS, 630090 Novosibirsk, Russia.
Oleg V BylinoLaboratory of Gene Expression Regulation in Development, Institute of Gene Biology RAS, 119334 Moscow, Russia.ORCID 0000-0002-8399-6194
Mikhail A BatinOpen Longevity, 15260 Ventura Blvd., Sherman Oaks, Los Angeles, CA 91403, USA.
Pavel G GeorgievLaboratory of Gene Expression Regulation in Development, Institute of Gene Biology RAS, 119334 Moscow, Russia.ORCID 0000-0002-6509-3194
Alexey V PindyurinDepartment of Regulation of Genetic Processes, Institute of Molecular and Cellular Biology SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0001-6959-0641
Institute of Gene Biology · RUInstitute of Molecular and Cell Biology · RUNovosibirsk State Agricultural University · RU

Funding

Russian Science Foundation 19-74-30026, 22-74-10118
6 · The paper itself

Abstract

The spatio-temporal regulation of gene expression determines the fate and function of various cells and tissues and, as a consequence, the correct development and functioning of complex organisms. Certain mechanisms of gene activity regulation provide adequate cell responses to changes in environmental factors. Aside from gene expression disorders that lead to various pathologies, alterations of expression of particular genes were shown to significantly decrease or increase the lifespan in a wide range of organisms from yeast to human.

Indexed as

Drosophila ProteinsLongevityAgingAnimalsDrosophilaDrosophila melanogasterHumansInsulinDrosophila ProteinsInsulinagingDrosophilagene expression regulationIISJNKlongevityNF-κBsignaling pathwayTOR

Identifiers

PMID36232546
PMCPMC9569508
OpenAlexW4297235477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.