Evidence map›Paper›PMID 36232532›Full record

ReviewInternational journal of molecular sciences2022

Landscape of Cellular Bioeffects Triggered by Ultrasound-Induced Sonoporation.

Dawid Przystupski, Marek Ussowicz

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  9. Review
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  13. Harnessing Ultrasonic Technologies to TreatMolecules (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dawid PrzystupskiDepartment of Paediatric Bone Marrow Transplantation, Oncology and Haematology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1706-3297
Marek UssowiczDepartment of Paediatric Bone Marrow Transplantation, Oncology and Haematology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

Funding

Ministry of Science and Higher Education 0074/DIA/2019/48
6 · The paper itself

Abstract

Sonoporation is the process of transient pore formation in the cell membrane triggered by ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation may assist cancer treatment through effective drug and gene delivery. However, there is a massive gap in the body of literature on the issue of understanding the complexity of biophysical and biochemical sonoporation-induced cellular effects. This study provides a detailed explanation of the US-triggered bioeffects, in particular, cell compartments and the internal environment of the cell, as well as the further consequences on cell reproduction and growth. Moreover, a detailed biophysical insight into US-provoked pore formation is presented. This study is expected to review the knowledge of cellular effects initiated by US-induced sonoporation and summarize the attempts at clinical implementation.

Indexed as

MicrobubblesSonicationCell MembraneCell Membrane PermeabilityGene Transfer Techniquescalcium signallingcancer cellscell deathDNA damagemechanotransductionmembrane permeabilizationmembrane resealingoxidative stresssonoporationultrasound

Identifiers

PMID36232532
PMCPMC9569453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.