Evidence map›Paper›PMID 36232449›Full record

ArticleInternational journal of molecular sciences2022

Metagenomic Sequencing for the Diagnosis of

Hagen Frickmann, Felix Weinreich, Ulrike Loderstädt, Sven Poppert, Egbert Tannich, Jana Bull, Bernd Kreikemeyer, Israel Barrantes

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Research on Plasmodium Infection and Immunity.International journal of molecular sciences · 2024
    Article
  4. Preanalytical, Analytical and Postanalytical Analyses onDiagnostics (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hagen FrickmannDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, Germany.ORCID 0000-0002-8967-9528
Felix WeinreichDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, Germany.ORCID 0000-0001-9173-7072
Ulrike LoderstädtDepartment of Hospital Hygiene & Infectious Diseases, University Medicine Göttingen, 37075 Goettingen, Germany.
Sven PoppertBernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany.ORCID 0000-0003-4873-249X
Egbert TannichBernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany.
Jana BullInstitute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.
Bernd KreikemeyerInstitute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0001-9527-5098
Israel BarrantesResearch Group Translational Bioinformatics, Institute for Biostatistics and Informatics in Medicine und Aging Research, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0002-5252-4485
Bernhard Nocht Institute for Tropical Medicine · DEBundeswehrkrankenhaus · DEUniversitätsmedizin Göttingen · DEUniversity of Rostock · DE

Funding

Federal Ministry of Defence 36K2-S-45 1922
6 · The paper itself

Abstract

Molecular diagnostic approaches are increasingly included in the diagnostic workup and even in the primary diagnosis of malaria in non-endemic settings, where it is difficult to maintain skillful microscopic malaria detection due to the rarity of the disease. Pathogen-specific nucleic acid amplification, however, bears the risk of overlooking other pathogens associated with febrile illness in returnees from the tropics. Here, we assessed the discriminatory potential of metagenomic sequencing for the identification of different

Indexed as

MalariaNucleic AcidsPlasmodiumEdetic AcidHumansParasitemiaPlasmodium falciparumPlasmodium vivaxReal-Time Polymerase Chain ReactionEdetic AcidNucleic Acidsgenomicsmixed infectionnext generation sequencingPlasmodium falciparumPlasmodium malariaePlasmodium ovale complexPlasmodium vivaxreturneetropics

Identifiers

PMID36232449
PMCPMC9569645
OpenAlexW4296848609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.