Evidence map›Paper›PMID 36232422›Full record

ArticleInternational journal of molecular sciences2022

A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines.

Alexander V Aksenov, Nikolai A Arutiunov, Dmitrii A Aksenov, Artem V Samovolov, Igor A Kurenkov, Nicolai A Aksenov, Elena A Aleksandrova, Daria S Momotova, Michael Rubin

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander V AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Nikolai A ArutiunovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Dmitrii A AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Artem V SamovolovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Igor A KurenkovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.ORCID 0000-0002-0911-4093
Nicolai A AksenovDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.ORCID 0000-0002-7125-9066
Elena A AleksandrovaDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Daria S MomotovaDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Michael RubinDepartment of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.ORCID 0000-0002-1668-9311

Funding

Russian Science Foundation 21-73-20051
6 · The paper itself

Abstract

Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves unusual extrusion of phenylacetonitrile molecule and could be performed in a short sequence starting from commonly available indoles and nitroolefins.

Indexed as

DiaminesQuinoxalinesAcetonitrilesBenzeneIndolesMolecular StructureAcetonitrilesBenzenebenzyl cyanideDiaminesIndolesQuinoxalinescyclizationmicrowave synthesisquinoxalines

Identifiers

PMID36232422
PMCPMC9570350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.