Evidence map›Paper›PMID 36232289›Full record

ArticleInternational journal of molecular sciences2022

The Impact of Spermidine on C2C12 Myoblasts Proliferation, Redox Status and Polyamines Metabolism under H

Roberta Ceci, Guglielmo Duranti, Stefano Giuliani, Marianna Nicoletta Rossi, Ivan Dimauro, Stefania Sabatini, Paolo Mariottini, Manuela Cervelli

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Ovarian aging: energy metabolism of oocytes.Journal of ovarian research · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Oxidative Stress and Skeletal Muscle Function.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Roberta CeciLaboratory of Biochemistry and Molecular Biology, Department of Movement, Human and Health Sciences, Università degli Studi di Roma "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-8900-8839
Guglielmo DurantiLaboratory of Biochemistry and Molecular Biology, Department of Movement, Human and Health Sciences, Università degli Studi di Roma "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-1664-9387
Stefano GiulianiDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.
Marianna Nicoletta RossiDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.ORCID 0000-0003-4485-7738
Ivan DimauroLaboratory of Biology and Genetics, Department of Movement, Human and Health Sciences, Università degli Studi di Roma "Foro Italico", 00135 Rome, Italy.ORCID 0000-0003-0577-3144
Stefania SabatiniLaboratory of Biochemistry and Molecular Biology, Department of Movement, Human and Health Sciences, Università degli Studi di Roma "Foro Italico", 00135 Rome, Italy.
Paolo MariottiniDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.ORCID 0000-0003-1044-7108
Manuela CervelliDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.ORCID 0000-0001-8535-8279
Foro Italico University of Rome · ITRoma Tre University · IT

Funding

Foro Italico University of Rome "Effects of spermine oxidase (SMOX) overexpression in skeletal muscle physiology and in pathological conditions."-CDR2.BANDO2017SS
6 · The paper itself

Abstract

A central feature of the skeletal muscle is its ability to regenerate through the activation, by environmental signals, of satellite cells. Once activated, these cells proliferate as myoblasts, and defects in this process profoundly affect the subsequent process of regeneration. High levels of reactive oxygen species such as hydrogen peroxide (H

Indexed as

Hydrogen PeroxideSpermidineAnimalsAntioxidantsCell ProliferationGlutathione DisulfideMiceMyoblastsOxidation-ReductionOxidoreductasesPolyaminesReactive Oxygen SpeciesAntioxidantsGlutathione DisulfideHydrogen PeroxideOxidoreductasesPolyaminesReactive Oxygen SpeciesSpermidineglutathionemyoblasts proliferationpolyamines homeostasisredox homeostasisspermidine

Identifiers

PMID36232289
PMCPMC9569770
OpenAlexW4296741587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.