SynthesisInternational journal of environmental research and public health2022
Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Do systematic reviews of non- and micro-invasive treatment for caries lesions in children and adolescents adhere to the PRISMA reporting guidelines? A meta-research.Evidence-based dentistry · 2026Pooled it
- Silver diamine fluoride versus atraumatic restorative treatment for management of childhood caries: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Mapping Systematic Reviews on the Management of Dental Caries in Primary Teeth: A Meta-research.Current pediatric reviews · 2026Pooled it
- Effects of light curing on silver diamine fluoride-treated carious lesions: A systematic review.PloS one · 2024Pooled it
- A randomized clinical trial of ammonia-free silver fluoride for treating cavitated dentine caries in primary teeth: adverse effects, short-term discolouration, and patient-reported outcomes.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Trial
- A Clinical Trial of 38% Silver Diamine Fluoride With Light Curing in Arresting Dentine Caries in Primary Teeth.International dental journal · 2025Trial
- Silver Diamine Fluoride in Oral Health Policy: A Strategic Pathway to Improve Access and Equity.Journal of public health dentistry · 2026Article
- Current practice, barriers and facilitators to caries management in children: a qualitative study in the Netherlands.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Effect of nanosilver fluoride versus silver diamine fluoride on shear bond strength and color change of resin-modified glass ionomer cement bonded to artificial dentin caries: an in-vitro study.BMC oral health · 2026Article
- Managing High-Risk Root Caries with Silver Diamine Fluoride Application: A Markov Simulation Study.Journal of health economics and outcomes research · 2026Article
- Oral hygiene agents at work: effects onFrontiers in cellular and infection microbiology · 2026Review
- Effectiveness of silver diamine fluoride in preventing and arresting dental caries in pediatric dentistry.Dental research journal · 2026Review
- Effect of Silver Diamine Fluoride Application Methods on Dentin Microhardness and Durability Under pH Cycling: An In Vitro Study.Clinical and experimental dental research · 2025Article
- Silver diamine fluoride versus sodium fluoride varnish in the treatment of proximal caries in primary molars: A randomized clinical trial.The Saudi dental journal · 2025Article
- Assessment of Trends in Non-Restorative and Preventative Dental Treatment Pre- and Post-COVID-19: A Health Informatics Pilot Study.Children (Basel, Switzerland) · 2025Article
- Article
- Training received, knowledge, and use of Silver Diamine Fluoride among Italian dentists: a nationwide survey.BMC oral health · 2025Article
- Revolutionizing adult oral care: Silver diamine fluoride's minimally invasive role.Bioinformation · 2025Article
- Cost-Effectiveness of Silver Diamine Fluoride Depends on Caries Activity: A Decision Analytic Model.Caries research · 2025Article
- Cariostatic Agents: From Silver Diamine Fluoride to Emerging Bioactive Compounds.Clinical, cosmetic and investigational dentistry · 2025Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A systematic review and meta-analysis were carried out to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in cavitated primary molars. A search for randomized and non-randomized trials with follow-up > 6 months was performed using PubMed, Scopus and Embase. The Cochrane risk of bias tools were used for the quality assessment. The success rate and odds ratios were chosen to calculate the effect size for the meta-analysis. A total of 792 papers were identified and 9 were selected. A high variability regarding SDF application protocol was found; otherwise, caries arrest was always recorded using visual/tactile methods. Two studies were judged at low risk of bias, six at moderate risk and one at high risk. Data from five studies were aggregated for meta-analysis. Heterogeneity was found moderate (I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.