Evidence map›Paper›PMID 36231716›Full record

ArticleInternational journal of environmental research and public health2022

Compliance to Guidelines in Prescribing Empirical Antibiotics for Individuals with Uncomplicated Urinary Tract Infection in a Primary Health Facility of Ghana, 2019-2021.

Helena Owusu, Pruthu Thekkur, Jacklyne Ashubwe-Jalemba, George Kwesi Hedidor, Oksana Corquaye, Asiwome Aggor, Allen Steele-Dadzie, Daniel Ankrah

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Helena OwusuPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Pruthu ThekkurCentre for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), 75001 Paris, France.ORCID 0000-0001-5257-5074
Jacklyne Ashubwe-JalembaMedwise Solutions, Nairobi P.O. Box 2356-00202 KNH, Kenya.ORCID 0000-0002-1451-2723
George Kwesi HedidorWorld Health Organization Country Office, Roman Ridge, Accra P.O. Box MB142, Ghana.ORCID 0000-0002-3147-5143
Oksana CorquayePharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Asiwome AggorPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Allen Steele-DadziePolyclinic/Family Medicine Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.
Daniel AnkrahPharmacy Department, Korle Bu Teaching Hospital, Accra P.O. Box KB77, Ghana.ORCID 0000-0002-2447-1830
Korle Bu Teaching Hospital · GHGhana Health Service · GHWorld Health Organization Regional Office for South-East Asia · IN

Funding

Department of HealthWorld Health Organization 001
6 · The paper itself

Abstract

Increasing trends in antimicrobial resistance among uropathogens call for rational use of empirical antibiotics for managing uncomplicated urinary tract infections (UTIs). In Ghana, standard treatment guidelines (STGs) for UTI recommend oral ciprofloxacin or cefuroxime for 5-7 days in females and 10-14 days in males. We conducted a cross-sectional audit using electronic medical records (EMR) to assess compliance to the STGs among adults (≥18 years) with uncomplicated UTIs diagnosed in a primary health facility between October 2019 and October 2021. Among 3717 patients, 71% were females and all had complete prescription details in the EMR. Of all the patients, 83% were prescribed empirical antibiotics, of whom 88% received oral ciprofloxacin or cefuroxime. Only 68% were prescribed antibiotics for the correct duration, which was significantly lower among males (10%) compared to females (90%). Among patients who received antibiotics, 60% were prescribed in line with the STGs. The results call for feedback to physicians about poor compliance to STGs with duration of antibiotic prescribed. Recommendations on 10-14 days duration of antibiotics for males needs to be reassessed and necessary amendments to STGs can be made. Leveraging the well-established EMR system, a real-time audit-feedback mechanism can be instituted to improve compliance with STGs.

Indexed as

Anti-Bacterial AgentsUrinary Tract InfectionsAdultCefuroximeCiprofloxacinCross-Sectional StudiesFemaleGhanaHealth FacilitiesHumansMaleAnti-Bacterial AgentsCefuroximeCiprofloxacinantimicrobial resistanceantimicrobial stewardshipaudit-feedback mechanismcomplianceelectronic medical recordsGhanaoperational researchsort iturinary tract infectionsWest Africa

Identifiers

PMID36231716
PMCPMC9566282
OpenAlexW4297977863

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.