Evidence map›Paper›PMID 36231509›Full record

ReviewInternational journal of environmental research and public health2022

Chlorpyrifos Occurrence and Toxicological Risk Assessment: A Review.

Elżbieta Wołejko, Bożena Łozowicka, Agata Jabłońska-Trypuć, Marta Pietruszyńska, Urszula Wydro

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
34.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 183 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Chlorpyrifos and Chlorpyrifos-Oxon: A Widening Spectrum of Toxicity.International journal of molecular sciences · 2026
    Review
  12. Article
  13. Toxicology research · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Protective effects ofToxicology research · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Elżbieta WołejkoDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45A Street, 15-351 Białystok, Poland.ORCID 0000-0001-8390-2947
Bożena ŁozowickaInstitute of Plant Protection-National Research Institute, Chełmońskiego 22 Street, 15-195 Białystok, Poland.
Agata Jabłońska-TrypućDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45A Street, 15-351 Białystok, Poland.ORCID 0000-0002-7711-3017
Marta PietruszyńskaDepartment of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24A Street, 15-276 Białystok, Poland.
Urszula WydroDepartment of Chemistry, Biology and Biotechnology, Bialystok University of Technology, Wiejska 45A Street, 15-351 Białystok, Poland.ORCID 0000-0001-6154-435X
Bialystok University of Technology · PLInstitute of Plant Protection · PLMedical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorpyrifos (CPF) was the most frequently used pesticide in food production in the European Union (EU) until 2020. Unfortunately, this compound is still being applied in other parts of the world. National monitoring of pesticides conducted in various countries indicates the presence of CPF in soil, food, and water, which may have toxic effects on consumers, farmers, and animal health. In addition, CPF may influence changes in the population of fungi, bacteria, and actinomycete in soil and can inhibit nitrogen mineralization. The mechanisms of CPF activity are based on the inhibition of acetylcholinesterase (AChE) activity. This compound also exhibits reproductive toxicity, neurotoxicity, and genotoxicity. The problem seems to be the discrepancy between the actual observations and the final conclusions drawn for the substance's approval in reports presenting the toxic impact of CPF on human health. Therefore, this influence is still a current and important issue that requires continuous monitoring despite its withdrawal from the market in the EU. This review traces the scientific reports describing the effects of CPF resulting in changes occurring in both the environment and at the cellular and tissue level in humans and animals. It also provides an insight into the hazards and risks to human health in food consumer products in which CPF has been detected.

Indexed as

ChlorpyrifosInsecticidesPesticidesAcetylcholinesteraseAnimalsHumansNitrogenSoilWaterAcetylcholinesteraseChlorpyrifosInsecticidesNitrogenPesticidesSoilWaterCPFenvironmentrisk assessmenttoxicity

Identifiers

PMID36231509
PMCPMC9566616
OpenAlexW4297539657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.