Evidence map›Paper›PMID 36231355›Full record

ReviewInternational journal of environmental research and public health2022

Hereditary Ovarian Cancer: Towards a Cost-Effective Prevention Strategy.

Aruni Ghose, Anita Bolina, Ishika Mahajan, Syed Ahmer Raza, Miranda Clarke, Abhinanda Pal, Elisabet Sanchez, Kathrine Sofia Rallis, Stergios Boussios

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Assessing the Clinical Relevance ofCurrent oncology (Toronto, Ont.) · 2026
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  15. Expression and clinical value of EIF3CL in serous ovarian cancer.The Journal of international medical research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 3 countries.

Aruni GhoseDepartment of Medical Oncology, Barts Cancer Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London E1 1BB, UK.ORCID 0000-0001-8332-8033
Anita BolinaDepartment of Medical Oncology, Clatterbridge Cancer Centre, Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool CH63 4JY, UK.ORCID 0000-0002-1890-7319
Ishika MahajanDepartment of Medical Oncology, Apollo Cancer Centre, Chennai 600001, India.ORCID 0000-0003-1640-7342
Syed Ahmer RazaDepartment of Internal Medicine, St. Thomas' Hospital, Guy's and St. Thomas' NHS Foundation Trust, London SE1 7EH, UK.ORCID 0000-0003-4716-3176
Miranda ClarkeDepartment of Internal Medicine, Royal London Hospital, Barts Health NHS Trust, London E1 1BB, UK.
Abhinanda PalDepartment of Internal Medicine, IQ City Medical College and Narayana Hospital, Durgapur 713206, India.
Elisabet SanchezDepartment of Medical Oncology, Medway NHS Foundation Trust, Gillingham ME7 5NY, UK.
Kathrine Sofia RallisCancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
Stergios BoussiosDepartment of Medical Oncology, Medway NHS Foundation Trust, Gillingham ME7 5NY, UK.ORCID 0000-0002-2512-6131
Apollo Proton Cancer Centre · INBarts Health NHS Trust · GBBeth Israel Deaconess Medical Center · USClatterbridge Cancer Centre NHS Foundation Trust · GBKing's College London · GBMedway NHS Foundation Trust · GBNarayan Medical College and Hospital · INSt Bartholomew's Hospital · GBSt Thomas' Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is the most lethal gynaecological malignancy. The search for a widely affordable and accessible screening strategy to reduce mortality from OC is still ongoing. This coupled with the late-stage presentation and poor prognosis harbours significant health-economic implications. OC is also the most heritable of all cancers, with an estimated 25% of cases having a hereditary predisposition. Advancements in technology have detected multiple mutations, with the majority affecting the

Indexed as

Breast NeoplasmsOvarian NeoplasmsCarcinoma, Ovarian EpithelialContraceptive AgentsCost-Benefit AnalysisFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseHumansMutationContraceptive AgentsBRCAcost effectivenessgenetic testingguidelinesovarian cancerrisk-reducing surgery

Identifiers

PMID36231355
PMCPMC9565024
OpenAlexW4297236193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.