ArticleInternational journal of environmental research and public health2022
Workplace Culture and Biomarkers of Health Risk.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Access to employer-supported paternity leave and workers' self-rated mental health - United States, 2024.Work (Reading, Mass.) · 2026Article
- Biological Sex as a Moderator of Work Determinants of Health: Implications for Work and Stress.Healthcare (Basel, Switzerland) · 2024Article
- Relationship Between Psychological Stress Scores and Urinary 5-HT Levels Over Time Under Psychological Stress.International journal of tryptophan research : IJTR · 2024Article
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Authors and funding
9 authors.
Funding
Abstract
Workplace culture has been studied for impact on health risk; however, connections with robust biologic markers of health remain to be established. We examined associations between the work environment and urinary levels of catecholamines and their metabolites as biomarkers of sympathetic nervous system activity, indicative of stress. We recruited participants (n = 219; 2018-2019) from a cardiovascular risk cohort to investigate workplace culture, well-being, and stress. Participants completed seven questionnaires. Urine samples were used to measure catecholamines and their metabolites by LC/MS/MS. Pearson correlation and linear regression models were used after adjusting for demographics and creatinine. Participants reporting higher well-being had lower urinary levels of dopamine, serotonin, and 3-methoxytyramine. Participants reporting a more engaged and more positive workplace had lower levels of dopamine and 3-methoxytyramine. Reported workplace isolation was correlated with higher levels of dopamine and 3-methoxytyramine. Given correlations between catecholamines, we used 3-methoxytyramine for linear regression. In fully adjusted models, in environments with a more positive culture, levels of 3-methoxytyramine remained lower (β = -0.065 ± 0.025,
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