ReviewInternational journal of environmental research and public health2022
Privacy-by-Design Environments for Large-Scale Health Research and Federated Learning from Data.
Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- From adolescence to Alzheimer's: a neurodevelopmental lifespan model of cognitive vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Trends and Long-Term Mortality in Sepsis: Evidence from a Population-Based Retrospective Cohort Study of 13,994 Hospitalizations in the Abruzzo Region, Central Italy.Antibiotics (Basel, Switzerland) · 2026Article
- Review
- Beyond the diagnostic threshold: paradigm shift in laboratory medicine from passive reaction to predictive capability.Frontiers in medicine · 2026Article
- Association between antihypertensive drugs and cancer risk: evidence from a population-based study in the Abruzzo region, Southern Italy.BMC cancer · 2025Article
- Digital twins, synthetic patient data, and in-silico trials: can they empower paediatric clinical trials?The Lancet. Digital health · 2025Review
- Twenty-year trend in comorbidity score among adults aged 50-85 years in Lombardy, Italy: Age-Cohort-Period analysis and future trends.BMJ open · 2025Observational
- Cost-effectiveness of outpatient adherence to recommendations for monitoring of patients hospitalized for heart failure.ESC heart failure · 2024Article
- Article
- Digital Biobanking and Big Data as a New Research Tool: A Position Paper.Healthcare (Basel, Switzerland) · 2023Article
- Disclosure control of machine learning models from trusted research environments (TRE): New challenges and opportunities.Heliyon · 2023Review
- Improved prediction of 5-year mortality by updating the chronic related score for risk profiling in the general population: lessons from the italian region of Lombardy.Frontiers in public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article offers a brief overview of 'privacy-by-design (or data-protection-by-design) research environments', namely Trusted Research Environments (TREs, most commonly used in the United Kingdom) and Personal Health Trains (PHTs, most commonly used in mainland Europe). These secure environments are designed to enable the safe analysis of multiple, linked (and often big) data sources, including sensitive personal data and data owned by, and distributed across, different institutions. They take data protection and privacy requirements into account from the very start (conception phase, during system design) rather than as an afterthought or 'patch' implemented at a later stage on top of an existing environment. TREs and PHTs are becoming increasingly important for conducting large-scale privacy-preserving health research and for enabling federated learning and discoveries from big healthcare datasets. The paper also presents select examples of successful TRE and PHT implementations and of large-scale studies that used them.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.