Evidence map›Paper›PMID 36231099›Full record

ArticleCells2022

The Toll-like Receptor 4 Polymorphism Asp299Gly Is Associated with an Increased Risk of Ovarian Cancer.

Katarzyna D Kania, Daria Haręża, Jacek R Wilczyński, Miłosz Wilczyński, Dariusz Jarych, Andrzej Malinowski, Edyta Paradowska

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  5. Impact of Sociodemographic, Clinical, and Genetic Factors andIranian journal of medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Katarzyna D KaniaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0002-0673-596X
Daria HarężaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.
Jacek R WilczyńskiDepartment of Surgical and Oncological Gynecology, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0000-0002-2072-6533
Miłosz WilczyńskiDepartment of Surgical, Endoscopic and Oncological Gynecology, Polish Mother's Health Center Research Institute, 93-338 Lodz, Poland.ORCID 0000-0002-5720-427X
Dariusz JarychLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0003-1303-7163
Andrzej MalinowskiDepartment of Surgical, Endoscopic and Oncological Gynecology, Polish Mother's Health Center Research Institute, 93-338 Lodz, Poland.
Edyta ParadowskaLaboratory of Virology, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0001-9446-0136
Polish Academy of Sciences · PLPolish Mother’s Memorial Hospital Research Institute · PLMedical University of Lodz · PLUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is one of the most common cancers threatening women's lives around the world. Epithelial ovarian tumors represent the most common ovarian neoplasms. Most OC patients are diagnosed at the advanced stage, and there is an urgent need to identify novel biomarkers of the disease. Single-nucleotide polymorphisms (SNPs) in

Indexed as

Ovarian NeoplasmsToll-Like Receptor 4BiomarkersCarcinoma, Ovarian EpithelialFemaleGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideToll-Like Receptor 9BiomarkersTLR4 protein, humanToll-Like Receptor 4Toll-Like Receptor 9human papillomavirusovarian cancersingle-nucleotide polymorphismtoll-like receptor

Identifiers

PMID36231099
PMCPMC9563956
OpenAlexW4303628438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.