Evidence map›Paper›PMID 36231074›Full record

ArticleCells2022

Withaferin a Attenuates Retinal Ischemia-Reperfusion Injury via Akt-Dependent Inhibition of Oxidative Stress.

Zheyi Yan, Yuanlin Zhang, Chunfang Wang, Yanjie Li, Qiang Su, Jimin Cao, Xiaoming Cao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. A review of protective effects ofFrontiers in pharmacology · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zheyi YanDepartment of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan 030001, China.
Yuanlin ZhangCollege of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine, Taiyuan 030619, China.
Chunfang WangDepartment of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan 030001, China.
Yanjie LiDepartment of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan 030001, China.
Qiang SuDepartment of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan 030001, China.
Jimin CaoKey Laboratory of Cellular Physiology, Ministry of Education, Department of Physiology, Shanxi Medical University, Taiyuan 030001, China.
Xiaoming CaoDepartment of Orthopedics, Shanxi Medical University Second Affiliated Hospital, Taiyuan 030000, China.
Shanxi Medical University · CNFirst Hospital of Shanxi Medical University · CNShanxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heme Oxygenase-1Reperfusion InjuryAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsEndothelial CellsHumansOxidative StressPeroxiredoxinsProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleyWithanolidesAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsHeme Oxygenase-1PeroxiredoxinsProto-Oncogene Proteins c-aktwithaferin AWithanolidesapoptosisendotheliumoxidative stressphytochemicalretinal ischemia-reperfusion injurywithaferin A

Identifiers

PMID36231074
PMCPMC9563317
OpenAlexW4303628739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.