Evidence map›Paper›PMID 36231067›Full record

ArticleCells2022

Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images.

Bálint Barna H Kovács, Dániel Varga, Dániel Sebők, Hajnalka Majoros, Róbert Polanek, Tibor Pankotai, Katalin Hideghéty, Ákos Kukovecz, Miklós Erdélyi

Abstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Cluster parameter-based DBSCAN maps for image characterization.Computational and structural biotechnology journal · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bálint Barna H KovácsDepartment of Optics and Quantum Electronics, University of Szeged, 6720 Szeged, Hungary.
Dániel VargaDepartment of Optics and Quantum Electronics, University of Szeged, 6720 Szeged, Hungary.
Dániel SebőkDepartment of Applied and Environmental Chemistry, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0001-9769-5598
Hajnalka MajorosInstitute of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, 6725 Szeged, Hungary.
Róbert PolanekBiomedical Applications Group, ELI-ALPS Research Institute, ELI-HU Non-Profit Ltd., 6728 Szeged, Hungary.ORCID 0000-0003-3645-8331
Tibor PankotaiInstitute of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, 6725 Szeged, Hungary.ORCID 0000-0001-9810-5465
Katalin HideghétyBiomedical Applications Group, ELI-ALPS Research Institute, ELI-HU Non-Profit Ltd., 6728 Szeged, Hungary.
Ákos KukoveczDepartment of Applied and Environmental Chemistry, University of Szeged, 6720 Szeged, Hungary.
Miklós ErdélyiDepartment of Optics and Quantum Electronics, University of Szeged, 6720 Szeged, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantitative analysis of datasets achieved by single molecule localization microscopy is vital for studying the structure of subcellular organizations. Cluster analysis has emerged as a multi-faceted tool in the structural analysis of localization datasets. However, the results it produces greatly depend on the set parameters, and the process can be computationally intensive. Here we present a new approach for structural analysis using lacunarity. Unlike cluster analysis, lacunarity can be calculated quickly while providing definitive information about the structure of the localizations. Using simulated data, we demonstrate how lacunarity results can be interpreted. We use these interpretations to compare our lacunarity analysis with our previous cluster analysis-based results in the field of DNA repair, showing the new algorithm's efficiency.

Indexed as

MicroscopySingle Molecule ImagingCluster AnalysisDNA RepairdSTORMlacunarityquantitative analysis

Identifiers

PMID36231067
PMCPMC9562870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.