Evidence map›Paper›PMID 36231023›Full record

ArticleCells2022

Restored Fyn Levels in Huntington's Disease Contributes to Enhanced Synaptic GluN2B-Composed NMDA Receptors and CREB Activity.

Lígia Fão, Patrícia Coelho, Ricardo J Rodrigues, A Cristina Rego

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lígia FãoCenter for Neuroscience and Cell Biology (CNC), University of Coimbra (Pólo I), Rua Larga, 3004-504 Coimbra, Portugal.ORCID 0000-0003-1497-7894
Patrícia CoelhoCenter for Neuroscience and Cell Biology (CNC), University of Coimbra (Pólo I), Rua Larga, 3004-504 Coimbra, Portugal.ORCID 0000-0002-8647-4658
Ricardo J RodriguesCenter for Neuroscience and Cell Biology (CNC), University of Coimbra (Pólo I), Rua Larga, 3004-504 Coimbra, Portugal.ORCID 0000-0002-7631-743X
A Cristina RegoCenter for Neuroscience and Cell Biology (CNC), University of Coimbra (Pólo I), Rua Larga, 3004-504 Coimbra, Portugal.ORCID 0000-0003-0700-3776
University of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Huntington DiseaseReceptors, N-Methyl-D-AspartateAnimalsCaspase 3Corpus StriatumCyclic AMP Response Element-Binding ProteinMiceProto-Oncogene Proteins c-fynCaspase 3Cyclic AMP Response Element-Binding ProteinFyn protein, mouseProto-Oncogene Proteins c-fynReceptors, N-Methyl-D-AspartateCREBfyn kinaseHuntington’s diseasemutant huntingtinNMDA receptorspost-synaptic density

Identifiers

PMID36231023
PMCPMC9563007
OpenAlexW4297973482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.