Evidence map›Paper›PMID 36230998›Full record

ArticleCells2022

Presynaptic 5-HT

Alice Taddeucci, Guendalina Olivero, Alessandra Roggeri, Claudio Milanese, Francesco Paolo Di Giorgio, Massimo Grilli, Mario Marchi, Beatrice Garrone, Anna Pittaluga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Schizophrenia: from mechanism to therapy.Science China. Life sciences · 2026
    Review
  2. No evidence for direct physical interaction of 5-HTbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. The crosstalk between 5-HTNeuropharmacology · 2023
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alice TaddeucciDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.
Guendalina OliveroDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.
Alessandra RoggeriDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.
Claudio MilaneseAngelini Pharma S.p.A., Viale America 70, 00181 Rome, Italy.
Francesco Paolo Di GiorgioAngelini Pharma S.p.A., Viale America 70, 00181 Rome, Italy.
Massimo GrilliDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.ORCID 0000-0003-1046-7897
Mario MarchiDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.
Beatrice GarroneAngelini Pharma S.p.A., Viale America 70, 00181 Rome, Italy.
Anna PittalugaDepartment of Pharmacy (DiFar), University of Genoa, Viale Cembrano 4, 16148 Genoa, Italy.ORCID 0000-0002-4011-1165
University of Genoa · ITAngelini Pharma (Italy) · ITOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glutamatergic nerve endings of a rat prefrontal cortex (PFc) possess presynaptic 5-HT

Indexed as

ClozapineReceptors, Metabotropic GlutamateTrazodoneAnimalsAutoreceptorsD-Aspartic AcidExocytosisGlutamic AcidKetanserinPrefrontal CortexRatsReceptor, Serotonin, 5-HT2ASerotoninAutoreceptorsClozapineD-Aspartic AcidGlutamic AcidKetanserinReceptor, Serotonin, 5-HT2AReceptors, Metabotropic GlutamateSerotoninTrazodone5-HT2A receptorclozapineglutamate exocytosismGlu2/3 receptorprefrontal cortexsynaptosomestrazodone

Identifiers

PMID36230998
PMCPMC9562019
OpenAlexW4297522390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.