Evidence map›Paper›PMID 36230983›Full record

ArticleCells2022

Identification of Metabolomics Biomarkers in Extracranial Carotid Artery Stenosis.

Chia-Ni Lin, Kai-Cheng Hsu, Kuo-Lun Huang, Wen-Cheng Huang, Yi-Lun Hung, Tsong-Hai Lee

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. SDMA as a marker and mediator in cerebrovascular disease.Clinical science (London, England : 1979) · 2024
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chia-Ni LinDepartment of Laboratory Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-2722-0164
Kai-Cheng HsuSchool of Medicine, College of Medicine, Artificial Intelligence Center for Medical Diagnosis, and Department of Neurology, China Medical University Hospital, Taichung 404327, Taiwan.
Kuo-Lun HuangStroke Center and Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0001-8215-721X
Wen-Cheng HuangDepartment of Nuclear Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Yi-Lun HungDepartment of Nuclear Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Tsong-Hai LeeStroke Center and Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Chang Gung University · TWLinkou Chang Gung Memorial Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biochemical identification of carotid artery stenosis (CAS) is still a challenge. Hence, 349 male subjects (176 normal controls and 173 stroke patients with extracranial CAS ≥ 50% diameter stenosis) were recruited. Blood samples were collected 14 days after stroke onset with no acute illness. Carotid plaque score (≥2, ≥5 and ≥8) was used to define CAS severity. Serum metabolites were analyzed using a targeted Absolute IDQ

Indexed as

Carotid StenosisStrokeAmino AcidsBiomarkersCholesterol, LDLGlycerophospholipidsHumansAmino AcidsBiomarkersCholesterol, LDLGlycerophospholipidscarotid artery stenosisdecision treeischemic strokemetabolomicsrandom forest

Identifiers

PMID36230983
PMCPMC9563778
OpenAlexW4297348482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.