Evidence map›Paper›PMID 36230948›Full record

ArticleCells2022

Modulation of Alveolar Macrophages by Postimmunobiotics: Impact on TLR3-Mediated Antiviral Respiratory Immunity.

Mikado Tomokiyo, Fernanda Raya Tonetti, Hikari Yamamuro, Ryoko Shibata, Kohtaro Fukuyama, Nadia Gobbato, Leonardo Albarracin, Muhammad Shahid Riaz Rajoka, A K M Humayun Kober, Wakako Ikeda-Ohtsubo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Prophylactic immune priming with heat-killedFrontiers in immunology · 2026
    Article
  2. Review
  3. ImmunobioticInternational journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Mikado TomokiyoFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Fernanda Raya TonettiLaboratory of Immunobiotechnology, Reference Centre for Lactobacilli CERELA-CONICET, San Miguel de Tucuman, Tucuman CP4000, Argentina.ORCID 0000-0002-8890-4252
Hikari YamamuroFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Ryoko ShibataFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Kohtaro FukuyamaFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Nadia GobbatoLaboratory of Immunology, Microbiology Institute, Faculty of Biochemestry, Chemestry and Pharmacy, National University of Tucuman, Tucuman CP4000, Argentina.
Leonardo AlbarracinFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.ORCID 0000-0001-8216-2190
Muhammad Shahid Riaz RajokaFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.ORCID 0000-0003-0137-4584
A K M Humayun KoberFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Wakako Ikeda-OhtsuboFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.
Julio VillenaFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.ORCID 0000-0003-4941-4960
Haruki KitazawaFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8576, Japan.ORCID 0000-0003-4586-5553
Tohoku University · JPCentro Científico Tecnológico - Tucumán · ARNational University of Tucumán · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beneficial microbes with immunomodulatory capacities (immunobiotics) and their non-viable forms (postimmunobiotics) could be effectively utilized in formulations towards the prevention of respiratory viral infections. In this study, novel immunobiotic strains with the ability to increase antiviral immunity in porcine alveolar macrophages were selected from a library of

Indexed as

Macrophages, AlveolarToll-Like Receptor 3AnimalsImmunity, InnateInterleukin-6MiceSwineInterleukin-6TLR3 protein, mouseToll-Like Receptor 3immunobioticsLactobacillus gasserilung inflammatory damageporcine alveolar macrophagespostimmunobioticsTLR3

Identifiers

PMID36230948
PMCPMC9562200
OpenAlexW4297152137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.