Evidence map›Paper›PMID 36230928›Full record

ReviewCells2022

Tracing Translational Footprint by Ribo-Seq: Principle, Workflow, and Applications to Understand the Mechanism of Human Diseases.

Atefeh Bagheri, Artem Astafev, Tara Al-Hashimy, Peng Jiang

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Molecular origin, discovery, validation and application of neoantigens.Asian journal of pharmaceutical sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Atefeh BagheriDepartment of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.
Artem AstafevDepartment of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.
Tara Al-HashimyDepartment of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.
Peng JiangDepartment of Biological, Geological and Environmental Sciences (BGES), Cleveland State University, Cleveland, OH 44115, USA.
Cleveland State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-seq has been widely used as a high-throughput method to characterize transcript dynamic changes in a broad context, such as development and diseases. However, whether RNA-seq-estimated transcriptional dynamics can be translated into protein level changes is largely unknown. Ribo-seq (Ribosome profiling) is an emerging technology that allows for the investigation of the translational footprint via profiling ribosome-bounded mRNA fragments. Ribo-seq coupled with RNA-seq will allow us to understand the transcriptional and translational control of the fundamental biological process and human diseases. This review focuses on discussing the principle, workflow, and applications of Ribo-seq to study human diseases.

Indexed as

RibosomesHumansRNA, MessengerRNA-SeqSequence Analysis, RNAWorkflowRNA, Messengerhuman diseasesribosome profilingtranslationtranslation efficiency (TE)

Identifiers

PMID36230928
PMCPMC9562884
OpenAlexW4297152192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.