ArticleCancers2022
Challenges in the Early Diagnosis of Oral Cancer, Evidence Gaps and Strategies for Improvement: A Scoping Review of Systematic Reviews.
Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06862414 (Application and Validation of a Smartphone-based Deep Learning System for Oral Potentially Malignant Disorders), which is not on this map. Cited by 98 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application and Validation of a Smartphone-based Deep Learning System for Oral Potentially Malignant Disorders (OPMD) and Oral Cancer Screening
Who cites it
98 citing papers in PubMed, 8 syntheses or guidelines pooled it, 156 citations in OpenAlex.
- Early Detection of Glottic Cancer Through Machine Learning and Acoustic Voice Analysis: A Systematic Review.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Patient and System Barriers to Early Diagnosis of Oral Cancer in the UK.Oral diseases · 2026Pooled it
- Crosstalk of the Hippo/YAP pathway in the progression of oral potentially malignant disorders to oral squamous cell carcinoma: a systematic review.Frontiers in oral health · 2026Pooled it
- Diagnosis of Oral Cancer With Deep Learning. A Comparative Test Accuracy Systematic Review.Oral diseases · 2025Pooled it
- Automated Detection of Oral Malignant Lesions Using Deep Learning: Scoping Review and Meta-Analysis.Oral diseases · 2025Pooled it
- Significance of Epidermal Growth Factor Receptor (EGFR) upregulation in the prediction of the malignant transformation risk in oral potentially malignant disorders: a systematic review and meta-analysis.Frontiers in oral health · 2025Pooled it
- Malignant transformation of oral leukoplakia: Systematic review and comprehensive meta-analysis.Oral diseases · 2025Pooled it
- The duration of intervals on the oral cancer care pathway and implications for survival: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Nanocarrier mediated microRNA delivery for oral squamous cell carcinoma a scoping review of delivery architecture preclinical efficacy and translational barriers.Discover nano · 2026Review
- Predictors of Lesion Detection in a 12-Year Oral Cancer Screening Program: A Cohort Study in Northern Portugal.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026Article
- Article
- Multi-class semantic segmentation of oral cancer tissues on whole-slide images: A SuperPixel enhanced deep learning approach.Journal of pathology informatics · 2026Article
- The oral microbiota in oral squamous cell carcinoma: unravelling mechanisms and clinical potential.Cancer cell international · 2026Review
- Article
- A Retrospective Analysis of the Diagnostic Accuracy in Diagnosing OPMD and Benign Oral Lesions.Oral diseases · 2026Article
- A comparative analysis of large language models for providing oral cavity cancer information.Scientific reports · 2026Article
- Artificial intelligence for diagnosis and triage in oral cancer: a clinician‑centered narrative review.International journal of clinical oncology · 2026Review
- Virtual assistants based on artificial intelligence for oral diagnosis: help for clinicians AI oral diagnosis helper.Diagnostic pathology · 2026Article
- Assessment of Interleukin-6 (IL-6) and Cotinine Levels in the Saliva of Patients with Precancerous Lesions and Oral Mucosa Cancer.Journal of clinical medicine · 2026Article
- An Analysis of the Timeline to Diagnosis and Treatment in Oral Cavity and Oropharynx Cancer.Oral diseases · 2026Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral cancer is a growing problem, accounting for 377,713 worldwide new cases per year, and 177,757 deaths annually and representing a 5-year mortality rate close to 50%, which is a considerable mortality that has not decreased substantially in the last 40 years. The main cause of this high mortality is related to the diagnosis of a high percentage of oral cancers in advanced stages (stages III and IV) in which treatment is complex, mutilating or disabling, and ineffective. The essential cause of a cancer diagnosis at a late stage is the delay in diagnosis, therefore, the achievement of the objective of improving the prognosis of oral cancer involves reducing the delay in its diagnosis. The reasons for the delay in the diagnosis of oral cancer are complex and involve several actors and circumstances-patients, health care providers, and health services. In this paper, we present the results of a scoping review of systematic reviews on the diagnostic delay in oral cancer with the aim to better understand, based on the evidence, and discuss in depth, the reasons for this fact, and to identify evidence gaps and formulate strategies for improvement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.