Evidence map›Paper›PMID 36230820›Full record

ArticleCancers2022

Identification of Predictive Factors for Overall Survival and Response during Hypomethylating Treatment in Very Elderly (≥75 Years) Acute Myeloid Leukemia Patients: A Multicenter Real-Life Experience.

Matteo Molica, Carla Mazzone, Pasquale Niscola, Ida Carmosino, Ambra Di Veroli, Cinzia De Gregoris, Fabrizio Bonanni, Salvatore Perrone, Natalia Cenfra, Luana Fianchi and 10 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Matteo MolicaHematology and Stem Cell Transplant Unit, St. Eugenio Hospital, 00144 Rome, Italy.ORCID 0000-0001-6391-4406
Carla MazzoneHematology and Stem Cell Transplant Unit, St. Eugenio Hospital, 00144 Rome, Italy.
Pasquale NiscolaHematology and Stem Cell Transplant Unit, St. Eugenio Hospital, 00144 Rome, Italy.ORCID 0000-0002-2226-6518
Ida CarmosinoHematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University, 00185 Rome, Italy.
Ambra Di VeroliHematology Division, Ospedale Belcolle, 01100 Viterbo, Italy.
Cinzia De GregorisHematology Division, Ospedale Belcolle, 01100 Viterbo, Italy.
Fabrizio BonanniHematology, Department of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.
Salvatore PerroneHematology, Polo Universitario Pontino, S.M. Goretti Hospital, 04100 Latina, Italy.ORCID 0000-0001-8196-0481
Natalia CenfraHematology, Polo Universitario Pontino, S.M. Goretti Hospital, 04100 Latina, Italy.
Luana FianchiInstitute of Hematology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Anna Lina PiccioniHematology and Stem Cell Transplant, San Giovanni Addolorata, 00184 Rome, Italy.
Antonio SpadeaHematology and Stem Cell Transplant Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Giovanni LuziHematology and Stem Cell Transplant, San Camillo Forlanini Hospital, 00152 Rome, Italy.
Andrea MengarelliHematology and Stem Cell Transplant Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0002-2606-2467
Laura CudilloHematology and Stem Cell Transplant, San Giovanni Addolorata, 00184 Rome, Italy.
Luca MaurilloHematology, Department of Biomedicine and Prevention, University Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-7297-4988
Livio PaganoInstitute of Hematology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8287-928X
Massimo BrecciaHematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-1163-6162
Luigi RigacciHematology and Stem Cell Transplant, San Camillo Forlanini Hospital, 00152 Rome, Italy.ORCID 0000-0002-9320-9334
Paolo De FabritiisHematology and Stem Cell Transplant Unit, St. Eugenio Hospital, 00144 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elderly patients represent the most challenging and hard-to-treat patient population due to dismal characteristics of the disease, such as secondary-acute myeloid leukemia (AML), enrichment of unfavorable molecular genes (

Indexed as

acute myeloid leukemiareal-life experiencevery elderly

Identifiers

PMID36230820
PMCPMC9564161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.