Evidence map›Paper›PMID 36230787›Full record

ReviewCancers2022

Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?

Imène Krossa, Thomas Strub, Andrew E Aplin, Robert Ballotti, Corine Bertolotto

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Epigenetic effects of herbal medicine.Clinical epigenetics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Imène KrossaUniversité Côte d'Azur, 06100 Nice, France.ORCID 0000-0003-0308-2024
Thomas StrubUniversité Côte d'Azur, 06100 Nice, France.
Andrew E AplinDepartment of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID 0000-0002-2734-3244
Robert BallottiUniversité Côte d'Azur, 06100 Nice, France.
Corine BertolottoUniversité Côte d'Azur, 06100 Nice, France.
Inserm · FRThomas Jefferson University · US

Funding

Fondation de France 00120250/WB-2021-33281Fondation pour la Recherche Médicale FRM ARF201809006989French National Cancer Institute INCA-16070Inserm NALigue Nationale Contre le Cancer NAMelanoma Research Alliance Team Science award NIH R01 CA253977
6 · The paper itself

Abstract

Epigenetic regulations, that comprise histone modifications and DNA methylation, are essential to processes as diverse as development and cancer. Among the histone post-translational modifications, lysine methylation represents one of the most important dynamic marks. Here, we focused on methyltransferases of the nuclear binding SET domain 1 (NSD) family, that catalyze the mono- and di-methylation of histone H3 lysine 36. We review the loss of function mutations of

Indexed as

cancersepigeneticsmelanomatherapies

Identifiers

PMID36230787
PMCPMC9563040
OpenAlexW4303621961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.