Evidence map›Paper›PMID 36230736›Full record

ReviewCancers2022

The Lung Microbiota and Lung Cancer: A Growing Relationship.

Maroun Bou Zerdan, Joseph Kassab, Paul Meouchy, Elio Haroun, Rami Nehme, Morgan Bou Zerdan, Gracia Fahed, Michael Petrosino, Dibyendu Dutta, Stephen Graziano

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Maroun Bou ZerdanDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USA.ORCID 0000-0002-9229-3079
Joseph KassabFaculty of Medicine, Saint-Joseph University, Beirut 11072180, Lebanon.ORCID 0000-0001-6761-7636
Paul MeouchyDepartment of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut 11072020, Lebanon.ORCID 0000-0002-5851-7411
Elio HarounDepartment of Medicine, Division of Hematology and Oncology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.ORCID 0000-0001-6230-0031
Rami NehmeDepartment of Medicine, University of Pavia, 27100 Pavia, Italy.
Morgan Bou ZerdanFaculty of Medicine, American University of Beirut, Beirut 11072020, Lebanon.
Gracia FahedFaculty of Medicine, American University of Beirut, Beirut 11072020, Lebanon.
Michael PetrosinoDepartment of Internal Medicine, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Dibyendu DuttaDepartment of Medicine, Division of Hematology and Oncology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Stephen GrazianoDepartment of Medicine, Division of Hematology and Oncology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
SUNY Upstate Medical University · USAmerican University of Beirut · LBAmerican University of Beirut Medical Center · LBSaint Joseph University · LBUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lung is home to a dynamic microbial population crucial to modulating immune balance. Interest in the role of the lung microbiota in disease pathogenesis and treatment has exponentially increased. In lung cancer, early studies suggested an important role of dysbiosis in tumor initiation and progression. These results have helped accelerate research into the lung microbiota as a potential diagnostic marker and therapeutic target. Microbiota signatures could represent diagnostic biomarkers of early-stage disease. Lung microbiota research is in its infancy with a limited number of studies and only single-center studies with a significant methodological variation. Large, multicenter longitudinal studies are needed to establish the clinical potential of this exciting field.

Indexed as

dysbiosisintestinal barrierlung cancermicrobiota

Identifiers

PMID36230736
PMCPMC9563611
OpenAlexW4303613678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.