Evidence map›Paper›PMID 36230689›Full record

ArticleCancers2022

Expression, Localization and Prognosis Association of MEP50 in Breast Cancer.

Samyuktha Suresh, Mathilde Vinet, Rayan Dakroub, Laetitia Lesage, Mengliang Ye, Hussein Fayyad-Kazan, André Nicolas, Didier Meseure, Thierry Dubois

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. The Role of WDR77 in Cancer: More than a PRMT5 Interactor.Molecular cancer research : MCR · 2025
    Review
  4. TBL2 Promotes Tumorigenesis via PRMT5/WDR77-Mediated AKT Activation in Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Samyuktha SureshBreast Cancer Biology Group, Translational Research Department, Institut Curie-PSL Research University, 75005 Paris, France.ORCID 0000-0001-8261-4097
Mathilde VinetBreast Cancer Biology Group, Translational Research Department, Institut Curie-PSL Research University, 75005 Paris, France.
Rayan DakroubBreast Cancer Biology Group, Translational Research Department, Institut Curie-PSL Research University, 75005 Paris, France.
Laetitia LesagePlatform of Experimental Pathology, Department of Diagnostic and Theranostic Medicine, Institut Curie-Hospital, 75005 Paris, France.ORCID 0000-0001-8592-2482
Mengliang YeBreast Cancer Biology Group, Translational Research Department, Institut Curie-PSL Research University, 75005 Paris, France.
Hussein Fayyad-KazanLaboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences-I, Lebanese University, Hadath 1003, Lebanon.ORCID 0000-0002-3465-4630
André NicolasPlatform of Experimental Pathology, Department of Diagnostic and Theranostic Medicine, Institut Curie-Hospital, 75005 Paris, France.
Didier MeseurePlatform of Experimental Pathology, Department of Diagnostic and Theranostic Medicine, Institut Curie-Hospital, 75005 Paris, France.
Thierry DuboisBreast Cancer Biology Group, Translational Research Department, Institut Curie-PSL Research University, 75005 Paris, France.ORCID 0000-0003-4739-6164
Université Paris Sciences et Lettres · FRInstitut Curie · FRLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is composed of distinct subgroups, triple-negative breast cancer (TNBC), human epidermal growth factor receptor-2 (HER2), luminal A, and luminal B, which are associated with different prognosis. MEP50 is the main partner of the arginine methyltransferase PRMT5 required for its enzymatic activity. Here, we examined

Indexed as

breast cancerepigeneticsH4R3me2sMEP50PRMT5prognosisrecurrence-free survivalTNBCtriple-negative breast cancer

Identifiers

PMID36230689
PMCPMC9563057
OpenAlexW4297982555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.