Evidence map›Paper›PMID 36230651›Full record

ReviewCancers2022

Survival Benefit of Adjuvant Chemotherapy in Pulmonary Carcinoid Tumors.

Philip T Sobash, Asad Ullah, Nagla Abdel Karim

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Atypical Carcinoid With Pulmonary Metastasis in an Adolescent.Annals of thoracic surgery short reports · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Philip T SobashGeorgia Cancer Center, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0001-9711-604X
Asad UllahDepartment of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0002-9435-9625
Nagla Abdel KarimInova Schar Cancer Institute, University of Virginia, Fairfax, VA 22031, USA.ORCID 0000-0002-8913-793X
Augusta University Health · USVanderbilt University Medical Center · USVirginia Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary carcinoid tumors are a rare subtype of neuroendocrine cell tumor found in approximately 1-2% of lung cancers. Management is primarily through surgical resection, with limited benefit of adjuvant therapy in the clinical setting. Genomic profiling is in the nascent stages to molecularly classify these tumors, but there are promising insights for future targeted therapy. A total of 80 abstracts were analyzed for further review with 11 included in our final analysis. Only 4 of the 11 reviewed in depth provided statistical analysis. We evaluated PFS, OS, 1- and 5-year survival as mentioned in the studies. Nodal and KI67 status were also analyzed. Based on the current literature, there is no definitive evidence that adjuvant chemotherapy after resection confers a survival benefit in typical or atypical carcinoids.

Indexed as

adjuvant chemotherapyatypical carcinoidneuroendocrine tumorpulmonary carcinoidsurvival benefit

Identifiers

PMID36230651
PMCPMC9564155
OpenAlexW4297464582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.