Evidence map›Paper›PMID 36230572›Full record

ArticleCancers2022

The Histone Demethylase HR Suppresses Breast Cancer Development through Enhanced CELF2 Tumor Suppressor Activity.

Yao Shen, Jasvinder Singh, Bindeshwar Sah, Zhongming Chen, Wootae Ha, Christine Henzler, Tao Su, Lillian Xie, Yibin Deng, Gen Li and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Yao ShenDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Jasvinder SinghThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Bindeshwar SahThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Zhongming ChenThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Wootae HaThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Christine HenzlerMinnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-4566-2211
Tao SuDepartment of Pathology, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0001-8672-9166
Lillian XieThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Yibin DengDepartment of Urology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Gen LiDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-7298-2141
Hua GuoDepartment of Pathology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Hanina HibshooshDepartment of Pathology, Columbia University Irving Medical Center, New York, NY 10032, USA.
Liang LiuThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.ORCID 0000-0001-7245-355X
University of Minnesota · USColumbia University Irving Medical Center · USUniversity of Michigan · USUniversity of Minnesota Medical Center · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Prevention of solar UV-induced skin cancer by targeting LTA4HR01CA196639 · NCI · UNIVERSITY OF MINNESOTA · PI LIU, LIANG · 2015 to 2019
$1.7M
Tensor Array Methods for RNA-Seq AnalysisR01HG010731 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LI, GEN · 2020 to 2024
$1.4M
Epigenetic control of target gene activity by hairless in skin homeostasisK01AR064315 · NIAMS · UNIVERSITY OF MINNESOTA · PI LIU, LIANG · 2014 to 2018
$582k
National Institute of Health P30CA013696NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA196639NHGRI NIH HHS R01 HG010731NIAMS NIH HHS K01 AR064315NIH HHS K01AR064315NIH HHS R01CA196639
6 · The paper itself

Abstract

The

Indexed as

breast cancerCELF2epigenetic therapyhairlesshistone methylation

Identifiers

PMID36230572
PMCPMC9564370
OpenAlexW4297148479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.