Evidence map›Paper›PMID 36230465›Full record

ArticleAnimals : an open access journal from MDPI2022

An Integrated Bioinformatics Approach to Identify Network-Derived Hub Genes in Starving Zebrafish.

Amin Mortazavi, Mostafa Ghaderi-Zefrehei, Mustafa Muhaghegh Dolatabady, Mahdi Golshan, Sajad Nazari, Ayeh Sadat Sadr, Saeid Kadkhodaei, Ikhide G Imumorin, Sunday O Peters, Jacqueline Smith

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Bayesian networks for network inference in biology.Journal of the Royal Society, Interface · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Amin MortazaviCold-Water Fishes Genetic and Breeding Research Center, Iranian Fisheries Research Institute, Agriculture Research Education and Extension Organization (AREEO), Yasouj 74394-75918, Iran.ORCID 0000-0001-9714-2897
Mostafa Ghaderi-ZefreheiDepartment of Animal Science, Faculty of Agriculture, Yasouj University, Yasouj 74394-75918, Iran.
Mustafa Muhaghegh DolatabadyDepartment of Animal Science, Faculty of Agriculture, Yasouj University, Yasouj 74394-75918, Iran.
Mahdi GolshanIranian Fisheries Research Institute, Agriculture Research Education and Extension Organization (AREEO), Tehran 14968-13151, Iran.
Sajad NazariCold-Water Fishes Genetic and Breeding Research Center, Iranian Fisheries Research Institute, Agriculture Research Education and Extension Organization (AREEO), Yasouj 74394-75918, Iran.
Ayeh Sadat SadrSouth of Iran Aquaculture Research Institute, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research Education and Extension Organization (AREEO), Ahvaz 19395-1113, Iran.
Saeid KadkhodaeiAgricultural Biotechnology Research Institute of Iran (ABRII), Center of Iran, Isfahan 14968-13151, Iran.
Ikhide G ImumorinSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Sunday O PetersDepartment of Animal Science, Berry College, Mount Berry, GA 30149, USA.ORCID 0000-0002-0216-926X
Jacqueline SmithThe Roslin Institute and Royal (Dick), School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.ORCID 0000-0002-2813-7872
Agricultural Research & Education Organization · IRYasouj University · IRAgricultural Biotechnology Research Institute of Iran · IRBerry College · USGeorgia Institute of Technology · USRoslin Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was aimed at identifying causative hub genes within modules formed by co-expression and protein-protein interaction (PPI) networks, followed by Bayesian network (BN) construction in the liver transcriptome of starved zebrafish. To this end, the GSE11107 and GSE112272 datasets from the GEO databases were downloaded and meta-analyzed using the MetaDE package, an add-on R package. Differentially expressed genes (DEGs) were identified based upon expression intensity N(µ = 0.2, σ

Indexed as

Bayesian networkbioinformatic analysisco-expressionhub genesstarvationzebrafish

Identifiers

PMID36230465
PMCPMC9559487
OpenAlexW4304128543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.