Evidence map›Paper›PMID 36229976›Full record

ArticleClinical and translational medicine2022

The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia.

Anton De Spiegeleer, Evelien Wynendaele, Amélie Descamps, Nathan Debunne, Bart P Braeckman, Marjan De Mey, Julie Coudenys, Liesbeth Crombez, Frederick Verbeke, Yorick Janssens and 17 more

Abstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Role of Peptides in Skeletal Muscle Wasting: A Scoping Review.Journal of cachexia, sarcopenia and muscle · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Anton De SpiegeleerTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-3681-2807
Evelien WynendaeleTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.
Amélie DescampsTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.
Nathan DebunneDrug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Bart P BraeckmanLaboratory for Aging Physiology and Molecular Evolution, Faculty of Sciences, Ghent University, Ghent, Belgium.
Marjan De MeyCenter for Synthetic Biology, Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Julie CoudenysTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.
Liesbeth CrombezTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.
Frederick VerbekeDrug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Yorick JanssensDrug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Rekin's JankyVIB Nucleomics Core, VIB, Leuven, Belgium.
Evy GoossensDepartment of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Caroline VlaeminckLaboratory for Aging Physiology and Molecular Evolution, Faculty of Sciences, Ghent University, Ghent, Belgium.
Dries DuchiCenter for Synthetic Biology, Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Vanessa AndriesVIB Center for Inflammation Research (IRC), Unit for Molecular Immunology and Inflammation, Ghent University, Ghent, Belgium.
Emilie DumasVIB Center for Inflammation Research (IRC), Unit for Molecular Immunology and Inflammation, Ghent University, Ghent, Belgium.
Mirko PetrovicDepartment of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent, Belgium.
Tom Van de WieleCenter for Microbial Ecology and Technology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Daniel KnappeCenter of Biotechnology and Biomedicine, Faculty of Chemistry and Mineralogy, University of Leipzig, Leipzig, Germany.
Ralf HoffmannCenter of Biotechnology and Biomedicine, Faculty of Chemistry and Mineralogy, University of Leipzig, Leipzig, Germany.
Vincent MoulyInstitut de Myologie, Centre de Recherche en Myologie, Inserm, Sorbonne Université, Paris, France.
Anne BigotInstitut de Myologie, Centre de Recherche en Myologie, Inserm, Sorbonne Université, Paris, France.
Lars VereeckeVIB Center for Inflammation Research (IRC), Unit for Molecular Immunology and Inflammation, Ghent University, Ghent, Belgium.
Filip Van ImmerseelHost-Microbiota-Interaction lab, VIB Center for Inflammation Research, Ghent, Belgium.
Nele Van Den NoortgateTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0001-5546-5380
Bart De SpiegeleerDrug Quality and Registration (DruQuaR) group, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.ORCID 0000-0001-6794-3108
Dirk ElewautTranslational Research in Immunosenescence, Gerontology and Geriatrics (TRIGG) group, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-7468-974X

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quorum SensingSarcopeniaBacteriaHumansOligopeptidesPeptidesOligopeptidesPeptidessex pheromone inhibitor iAM373

Identifiers

PMID36229976
PMCPMC9561422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.