ArticleClinical cardiology2023
Sex-specific risk factors of carotid atherosclerosis progression in a high-risk population of cardiovascular disease.
Article in Clinical cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Impact of alcohol consumption on atherosclerosis: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Assessing the Prognostic Significance of Ultrasound - Detected Carotid Plaque Morphology in Predicting Ischemic Stroke Risk Among Postmenopausal Women.International journal of women's health · 2026Article
- Reliability of B-mode ultrasound measurement of carotid intima-media thickness in assessing cardiovascular risk: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Endothelial Dysfunction in Sex-Specific Disparities in Cardiovascular Diseases: Biological Mechanisms, Diagnostic-Therapeutic Differences, and Translational Medicine Strategies.Reviews in cardiovascular medicine · 2025Review
- Biological Sex and the Association Between Grip Strength and Cardiovascular Disease: a Scoping Review.Canadian geriatrics journal : CGJ · 2025Review
- Influencing and prognostic factors of end-stage hypertrophic cardiomyopathy.ESC heart failure · 2024Article
- Age and Sex Differences in Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Analysis of risk factors for carotid artery plaque in asymptomatic adults.BMC cardiovascular disorders · 2024Article
- Healthy lifestyles and rapid progression of carotid plaque in population with atherosclerosis: A prospective cohort study in China.Preventive medicine reports · 2024Article
- Risk Factors for Medial and Intimal Intracranial Internal Carotid Artery Calcification in Men and Women with Cardiovascular Disease: The UCC-SMART Study.Cerebrovascular diseases (Basel, Switzerland) · 2024Article
- Why and How Should We Assess the Cardiovascular Risk in Patients with Juvenile Idiopathic Arthritis? A Single-Centre Experience with Carotid Intima-Media Measurements.Children (Basel, Switzerland) · 2023Article
- Sex-specific risk factors of carotid atherosclerosis progression in a high-risk population of cardiovascular disease.Clinical cardiology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe progression of carotid intima-media thickness (cIMT) and plaques are associated with cardiovascular health, especially for high-risk population of cardiovascular disease (CVD). HYPOTHESIS: Risk factors for atherosclerosis may vary by sex. This study aimed to investigate the sex-specific risk factors of cIMT and plaque progression.
methodsWe selected subjects who were identified as high-risk population of CVD, and collected their carotid ultrasound data and baseline characteristics. Linear regression and logistic regression analyses were used to identify risk factors for cIMT and plaque progression. Sex-specific risk factors were identified respectively.
resultsA total of 7908 participants were included. The mean age was 57.75 ± 9.45 years and 61.51% were female. During mean follow-up of 1.92 ± 0.89 years, the median annual cIMT change rate was -7.25 μm/year. Seven hundred and fifteen subjects free from plaques at baseline developed plaque. Age, smoking, hypertension, and diabetes were common risk factors for carotid atherosclerosis progression in all participants. Smoking and alcohol drinking were significantly associated with increased cIMT change in women, while hypertension and antihypertensive medication were significant in men. Increased total cholesterol and diabetes were significantly associated with new plaque presence in women, while smoking, increased triglyceride, and dyslipidemia were significant in men (p ˂ .05 for all cases). The association of baseline cIMT and smoking with annual cIMT change rate and increased total cholesterol with new plaque presence were significantly differentiated between both sexes (p for interaction ˂ .05).
conclusionsThe risk factors for cIMT and plaque progression differed by sex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.