ArticleCardiovascular diabetology2022
Association between metabolically healthy obesity and risk of atrial fibrillation: taking physical activity into consideration.
Article in Cardiovascular diabetology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 15 citations in OpenAlex.
- Association of Physical Activity With All-Cause and CVD Mortality Across Metabolic and Obesity Phenotypes.Diabetes, obesity & metabolism · 2026Article
- Association between the triglyceride-high-density lipoprotein-glucose-body index and atrial fibrillation: a retrospective case-control study.Frontiers in nutrition · 2026Article
- Changes in physical activity before and after the diagnosis of dyslipidemia and the risk of atrial fibrillation: a population-based study in South Korea.Preventive medicine reports · 2025Article
- Association of Body Mass Index and Metabolic Health Status With Cerebrovascular Diseases in 617 755 Chinese Older People.Journal of the American Heart Association · 2025Article
- Risk of Adverse Events in Anticoagulated Patients With Atrial Fibrillation and Nonalcoholic Fatty Liver Disease.The Journal of clinical endocrinology and metabolism · 2024Article
- Article
- Elevated remnant cholesterol was associated with the increased metabolically unhealthy obesity risk in Chinese youth.Asia Pacific journal of clinical nutrition · 2024Article
- Associations between life's essential 8 and metabolic health among us adults: insights of NHANES from 2005 to 2018.Acta diabetologica · 2024Article
- Racial and Gender Differences in Cardiorespiratory Fitness and Atrial Fibrillation.Reviews in cardiovascular medicine · 2024Review
- Relationship between metabolic status, physical activity and cardiovascular disease in participants with obesity.International journal of obesity (2005) · 2024Article
- Exploring metabolically healthy obesity: prevalence, characteristics, and cardiovascular risk in the Iranian population based on the STEPS 2021.Journal of diabetes and metabolic disorders · 2024Article
- Trends and characteristics of the metabolically healthy obese phenotype in an Arab population.Frontiers in public health · 2024Article
- Effect of physical exercise on metabolism in patients with atrial fibrillation.Frontiers in cardiovascular medicine · 2024Review
- Analysis Using Various Models on the Effect of Metabolic Surgery on Cardiovascular Disease Risk in the Chinese Population with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management.Reviews in endocrine & metabolic disorders · 2023Review
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Authors and funding
7 authors at 6 institutions in 4 countries.
Funding
Abstract
The modification of physical activity (PA) on the metabolic status in relation to atrial fibrillation (AF) in obesity remains unknown. We aimed to investigate the independent and joint associations of metabolic status and PA with the risk of AF in obese population. Based on the data from UK Biobank study, we used Cox proportional hazards models for analyses. Metabolic status was categorized into metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). PA was categorized into four groups according to the level of moderate-to-vigorous PA (MVPA): none, low, medium, and high. A total of 119,424 obese participants were included for analyses. MHO was significantly associated with a 35% reduced AF risk compared with MUO (HR = 0.65, 95% CI: 0.57-0.73). No significant modification of PA on AF risk among individuals with MHO was found. Among the MUO participants, individuals with medium and high PA had significantly lower AF risk compared with no MVPA (HR = 0.84, 95% CI: 0.74-0.95, and HR = 0.87, 95% CI: 0.78-0.96 for medium and high PA, respectively). As the severity of MUO increased, the modification of PA on AF risk was elevated accordingly. To conclude, MHO was significantly associated with a reduced risk of AF when compared with MUO in obese participants. PA could significantly modify the relationship between metabolic status and risk of AF among MUO participants, with particular benefits of PA associated with the reduced AF risk as the MUO severity elevated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.