Evidence map›Paper›PMID 36229642›Full record

ArticleInternational journal of obesity (2005)2022

Sex as an independent variable in the measurement of satiation: a retrospective cohort study.

Maria D Hurtado, Lizeth Cifuentes, Alejandro Campos, Alan De La Rosa, Ekta Kapoor, Stephanie S Faubion, Donald D Hensrud, Michael Camilleri, Andres Acosta

Abstract read
In one paragraph

Article in International journal of obesity (2005), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria D HurtadoDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, 4500 San Pablo Rd S, Jacksonville, FL, 32224, USA.ORCID 0000-0002-2322-7334
Lizeth CifuentesPrecision Medicine for Obesity Program, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0001-7865-2947
Alejandro CamposPrecision Medicine for Obesity Program, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0002-6294-8652
Alan De La RosaPrecision Medicine for Obesity Program, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Ekta KapoorCenter for Women's Health, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Stephanie S FaubionCenter for Women's Health, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Donald D HensrudDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.
Michael CamilleriDivision of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA.ORCID 0000-0001-6472-7514
Andres AcostaPrecision Medicine for Obesity Program, Mayo Clinic, 200 1st St SW, Rochester, MN, 55905, USA. acosta.andres@mayo.edu.ORCID 0000-0003-2286-489X

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's DiseaseU54AG044170 · NIA · MAYO CLINIC ROCHESTER · PI KAPOOR, EKTA · 2018 to 2022
$7.7M
Sex-specific Risk for Vascular Dysfunction and Cognitive DeclineP50AG044170 · NIA · MAYO CLINIC ROCHESTER · PI MILLER, VIRGINIA M · 2012 to 2017
$6.1M
Pharmacogenomics of Gastric Function &Weight in ObesityR01DK067071 · NIDDK · MAYO CLINIC ROCHESTER · PI CAMILLERI, MICHAEL L. · 2004 to 2020
$4.7M
Mechanisms of Enteroendocrine L-Cell Dysfunction and Bile Adaptations to Weight LossK23DK114460 · NIDDK · MAYO CLINIC ROCHESTER · PI ACOSTA, ANDRES J · 2018 to 2022
$980k
NCATS NIH HHS UL1 TR000135NIA NIH HHS P50 AG044170NIA NIH HHS U54 AG044170NIDDK NIH HHS K23 DK114460NIDDK NIH HHS R01 DK067071
6 · The paper itself

Abstract

backgroundSatiation is a key component of food intake regulation as it brings an eating episode to an end. The effect of sex on satiation measurement has not been characterized.

objectiveTo assess the effects of biological variables on satiation.

designRetrospective cohort study. We included 959 participants (mean age 39 [SD 12] years; 70.7% female, and BMI 33 kg/m

resultsFemales had higher BMI, W/H, and LM%. VTF, MTV, and CTF were lower in females: 704 [323] vs. 783 [328] mL, p = 0.001; 1226 [384] vs. 1419 [410] mL, p < 0.001; and 871 [291] vs. 1086 [326] kcal, p < 0.001; respectively. Sex was a strong and independent predictor of VTF, MTF and CTF: parameter estimate [PE] = -80.8, p = 0.006; PE = -124.2, p = 0.0007; and PE = -110, p = 0.001; respectively.

conclusionsSex has a strong effect on satiation measured by VTF, MTV, and CTF, even after adjusting for other biological factors known to affect these parameters. Females seem to integrate intra-meal inhibition signals to consume fewer calories unrelated to body size or composition. CLINICAL

trial registrationNone.

Indexed as

ObesitySatiationAdultEatingEnergy IntakeFemaleHumansMaleMealsRetrospective Studies

Identifiers

PMID36229642
PMCPMC9912571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.