Evidence map›Paper›PMID 36229588›Full record

ArticleIrish journal of medical science2023

Breast cancer risk coordinators: Artificial intelligence-based density measurement and Mullerian-inhibiting substance.

Şevki Pedük, Sevcan Sarıkaya, Mustafa Tekin

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Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Şevki PedükSancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, Surgical Oncology, Emek District Namık Kemal Street N: 54, 34785, Sancaktepe, Turkey. hagariii@gmail.com.ORCID http://orcid.org/0000-0002-7476-384X
Sevcan SarıkayaKonya City Hospital - Gynecology and Obstetrics, Karatay, Turkey.ORCID http://orcid.org/0000-0002-0922-4671
Mustafa TekinAksaray University Training and Research Hospital - Gynecology and Obstetrics, Aksaray, Turkey.ORCID http://orcid.org/0000-0002-7339-0324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to its increasing prevalence, breast cancer has become a serious public health problem. In addition to the models used to identify individuals at risk, the search for fast and accurate tools has continued for years.

aimsIn our study, we aimed to examine the correlation of mammographic density measurement and serum Mullerian-inhibiting substance (MIS) levels with an effective model such as Gail.

methodsOf the women whose serum MIS levels were measured in the last 1 year, 214 participants who applied for routine breast examination were included in the study. The age range was between 40 and 60. Exclusion criteria were determined as pathological mammographic findings, active breast symptom, and thoracic radiotherapy history. Mammographic density measurement (PD) was performed with the artificial intelligence-based Deep-LIBRA software. The relationship of these two parameters with the lifetime risk of developing breast cancer was examined.

resultsThe correlation between PD and GRP was remarkable (p < 0.01 cc:0.35). A positive correlation was observed between serum MIS levels and increased breast cancer, but it was not possible to prove this statistically (p = 0.056). It was thought that this situation was caused by perimenopausal patients. Because when the menopause group was excluded, the correlation between MIS levels and GRP decreased (p = 0.12 cc:0.17).

conclusionsPD measurement can be considered as a promising method for the determination of individuals at risk for breast cancer in a large group of patients, but we think that serum MIS levels are not suitable for risk assessment in perimenopausal patients.

Indexed as

Breast NeoplasmsAnti-Mullerian HormoneArtificial IntelligenceBreastFemaleHumansMammographyRisk FactorsAnti-Mullerian HormoneBreast densityBreast neoplasmsMammographyMullerian-inhibiting substance

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.