Evidence map›Paper›PMID 36229556›Full record

GuidelineSurgical endoscopy2022

EAES rapid guideline: updated systematic review, network meta-analysis, CINeMA and GRADE assessment, and evidence-informed European recommendations on the management of common bile duct stones.

Luigi Boni, Bright Huo, Laura Alberici, Claudio Ricci, Sofia Tsokani, Dimitris Mavridis, Yasser Sami Amer, Alexandros Andreou, Thomas Berriman, Gianfranco Donatelli and 8 more

Abstract readNetwork Meta-AnalysisPractice GuidelineSystematic Review
PubMed Publisher
In one paragraph

Guideline in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Porcelain gallbladder revisited.Journal of ultrasound · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Luigi BoniDepartment of Surgery, Fondazione IRCCS Ca' Granda Ospedale Maggiore, Policlinico di Milano, Milan, Italy.
Bright HuoFaculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Laura AlbericiDivision of Pancreatic Surgery, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Claudio RicciDivision of Pancreatic Surgery, IRCCS, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Sofia TsokaniDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Dimitris MavridisDepartment of Primary Education, School of Education, University of Ioannina, Ioannina, Greece.
Yasser Sami AmerPediatrics Department, and Clinical Practice Guidelines and Quality Research Unit, Quality Management Department, King Saud University Medical City, Riyadh, Saudi Arabia.
Alexandros AndreouDepartment of Surgery, York Teaching Hospital NHS Foundation Trust, York, UK.
Thomas BerrimanDepartment of Gastroenterology, York Teaching Hospital NHS Foundation Trust, York, UK.
Gianfranco DonatelliHôpital Privé Des Peupliers, Unité d'Endoscopie Interventionnelle, Ramsay Santé, Paris, France.
Nauzer ForbesDepartment of Medicine, University of Calgary, Calgary, AB, Canada.
Stylianos KapirisThird Department of Surgery, Evangelismos General Hospital, Athens, Greece.
Cüneyt KayaalpGastrointestinal Surgery, Yeditepe University Medical School, Istanbul, Turkey.
Leena KylänpääDepartment of Gastrointestinal Surgery, Helsinki University Hospital, Helsinki, Finland.
Pablo Parra-MembrivesDepartment of General and Digestive Surgery, Valme University Hospital, Seville, Spain.
Peter D SiersemaDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, Netherlands.
George F BlackPatient Representative, Siloam Springs, Arkansas, USA.
Stavros A AntoniouEuropean University Cyprus, Nicosia, Cyprus. guidelines@eaes.eu.ORCID http://orcid.org/0000-0002-4630-6748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCholedocholithiasis presents in a considerable proportion of patients with gallbladder disease. There are several management options, including preoperative or intraoperative endoscopic cholangiopancreatography (ERCP), and laparoscopic common bile duct exploration (LCBDE).

objectiveTo develop evidence-informed, interdisciplinary, European recommendations on the management of common bile duct stones in the context of intact gallbladder with a clinical decision to intervene to both the gallbladder and the common bile duct stones.

methodsWe updated a systematic review and network meta-analysis of LCBDE, preoperative, intraoperative, and postoperative ERCP. We formed evidence summaries using the GRADE and the CINeMA methodology, and a panel of general surgeons, gastroenterologists, and a patient representative contributed to the development of a GRADE evidence-to-decision framework to select among multiple interventions.

resultsThe panel reached unanimous consensus on the first Delphi round. We suggest LCBDE over preoperative, intraoperative, or postoperative ERCP, when surgical experience and expertise are available; intraoperative ERCP over LCBDE, preoperative or postoperative ERCP, when this is logistically feasible in a given healthcare setting; and preoperative ERCP over LCBDE or postoperative ERCP, when intraoperative ERCP is not feasible and there is insufficient experience or expertise with LCBDE (weak recommendation). The evidence summaries and decision aids are available on the platform MAGICapp ( https://app.magicapp.org/#/guideline/nJ5zyL ).

conclusionWe developed a rapid guideline on the management of common bile duct stones in line with latest methodological standards. It can be used by healthcare professionals and other stakeholders to inform clinical and policy decisions. GUIDELINE REGISTRATION NUMBER: IPGRP-2022CN170.

Indexed as

Cholecystectomy, LaparoscopicCholedocholithiasisGallstonesCholangiopancreatography, Endoscopic RetrogradeCommon Bile DuctGRADE ApproachHumansMotion PicturesAGREE-SCholedocholithiasisCommon bile duct stonesERCPGuidelinesLaparoscopic common bile duct exploration

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.