ArticleScientific reports2022
Immediate protein expression from exogenous mRNAs in embryonic brain.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Design of an automated cell batch microinjection system based on magnetic tweezers for zebrafish embryos.Microsystems & nanoengineering · 2026Article
- Design and developing a robot-assisted cell batch microinjection system for zebrafish embryo.Microsystems & nanoengineering · 2025Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
mRNA vaccines for SARS-CoV-2 have been widely used and saving millions of people in the world. How efficiently proteins are produced from exogenous mRNAs in the embryonic brain, however, is less known. Here we show that protein expression occurs highly efficiently in neural stem cells, in a very narrow time window after mRNA electroporation in the embryonic mouse brain, where plasmids have been successfully transfected. Protein expression is detected 1 h and 12 h after the electroporation of mRNAs and plasmids, respectively. The delivery of exogenous mRNAs may be useful for not only vaccines but also functional analysis in the brain.
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