Evidence map›Paper›PMID 36229469›Full record

ArticleNature communications2022

Spatiotemporal variations in retrovirus-host interactions among Darwin's finches.

Jason Hill, Mette Lillie, Mats E Pettersson, Carl-Johan Rubin, B Rosemary Grant, Peter R Grant, Leif Andersson, Patric Jern

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jason Hill *Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden. jason.hill@imbim.uu.se.ORCID 0000-0002-0151-8931
Mette Lillie *Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden. mette.lillie@imbim.uu.se.ORCID 0000-0001-8714-0812
Mats E PetterssonScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden.ORCID 0000-0002-7372-9076
Carl-Johan RubinScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden.ORCID 0000-0001-8238-5052
B Rosemary GrantDepartment of Ecology & Evolutionary Biology, Princeton University, Princeton, NJ, 08544, USA.
Peter R GrantDepartment of Ecology & Evolutionary Biology, Princeton University, Princeton, NJ, 08544, USA.
Leif AnderssonScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden.ORCID 0000-0002-4085-6968
Patric JernScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Uppsala, Sweden. Patric.Jern@imbim.uu.se.ORCID 0000-0003-3393-5825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous retroviruses (ERVs) are inherited remnants of retroviruses that colonized host germline over millions of years, providing a sampling of retroviral diversity across time. Here, we utilize the strength of Darwin's finches, a system synonymous with evolutionary studies, for investigating ERV history, revealing recent retrovirus-host interactions in natural populations. By mapping ERV variation across all species of Darwin's finches and comparing with outgroup species, we highlight geographical and historical patterns of retrovirus-host occurrence, utilizing the system for evaluating the extent and timing of retroviral activity in hosts undergoing adaptive radiation and colonization of new environments. We find shared ERVs among all samples indicating retrovirus-host associations pre-dating host speciation, as well as considerable ERV variation across populations of the entire Darwin's finches' radiation. Unexpected ERV variation in finch species on different islands suggests historical changes in gene flow and selection. Non-random distribution of ERVs along and between chromosomes, and across finch species, suggests association between ERV accumulation and the rapid speciation of Darwin's finches.

Indexed as

Endogenous RetrovirusesFinchesPasseriformesAnimalsBiological EvolutionEcuadorGene FlowPhylogeny

Identifiers

PMID36229469
PMCPMC9562234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.