ArticleNature communications2022
Spatially structured eco-evolutionary dynamics in a host-pathogen interaction render isolated populations vulnerable to disease.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Harnessing plant-to-plant signalling via common mycorrhizal networks for enhanced community-level resistance in crops.Journal of experimental botany · 2026Review
- Holocene man-occupied caves and transformed wetlands as facilitating factors for Leishmania infantum in South America.Memorias do Instituto Oswaldo Cruz · 2026Article
- How Population Structure and Nest Membership Shape Pathogen Patterns in Bumble Bees.Molecular ecology · 2025Article
- Landscape structure as a driver of eco-evolution in host-parasite systems.Evolution letters · 2025Article
- Home-based physical activity and well-being during infectious diseases: a structural equation modeling study.Frontiers in psychology · 2025Article
- A pathogen's spatial range is not constrained by geographical features in the flax rust pathosystem.Ecology and evolution · 2023Article
- The first arriving virus shapes within-host viral diversity during natural epidemics.Proceedings. Biological sciences · 2023Article
- How do fluctuating ecological dynamics impact the evolution of hosts and parasites?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Spatially structured eco-evolutionary dynamics in a host-pathogen interaction render isolated populations vulnerable to disease.Nature communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
While the negative effects that pathogens have on their hosts are well-documented in humans and agricultural systems, direct evidence of pathogen-driven impacts in wild host populations is scarce and mixed. Here, to determine how the strength of pathogen-imposed selection depends on spatial structure, we analyze growth rates across approximately 4000 host populations of a perennial plant through time coupled with data on pathogen presence-absence. We find that infection decreases growth more in the isolated than well-connected host populations. Our inoculation study reveals isolated populations to be highly susceptible to disease while connected host populations support the highest levels of resistance diversity, regardless of their disease history. A spatial eco-evolutionary model predicts that non-linearity in the costs to resistance may be critical in determining this pattern. Overall, evolutionary feedbacks define the ecological impacts of disease in spatially structured systems with host gene flow being more important than disease history in determining the outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.