Evidence map›Paper›PMID 36229338›Full record

ArticleJournal of optometry2022

Development and validation of a pixel wise deep learning model to detect cataract on swept-source optical coherence tomography images.

Pierre Zéboulon, Christophe Panthier, Hélène Rouger, Jacques Bijon, Wassim Ghazal, Damien Gatinel

Abstract read
In one paragraph

Article in Journal of optometry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pierre ZéboulonDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France. Electronic address: pzeboulon@for.paris.
Christophe PanthierDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France.
Hélène RougerDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France.
Jacques BijonDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France.
Wassim GhazalDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France.
Damien GatinelDepartment of Ophthalmology, Rothschild Foundation, 25 Rue Manin, Paris 75019, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe diagnosis of cataract is mostly clinical and there is a lack of objective and specific tool to detect and grade it automatically. The goal of this study was to develop and validate a deep learning model to detect and localize cataract on Swept Source Optical Coherance Tomography (SS-OCT) images.

methodsWe trained a convolutional network to detect cataract at the pixel level from 504 SS-OCT images of clear lens and cataract patients. The model was then validated on 1326 different images of 114 patients. The output of the model is a map repreenting the probability of cataract for each pixel of the image. We calculated the Cataract Fraction (CF), defined as the number of pixel classified as "cataract" divided by the number of pixel representing the lens for each image. Receiver Operating Characteristic Curves were plotted. Area Under the Curve (ROC AUC) sensitivity and specitivity to detect cataract were calculated.

resultsIn the validsation set, mean CF was 0.024 ± 0.077 and 0.479 ± 0.230 (p < 0.001). ROC AUC was 0.98 with an optimal CF threshold of 0.14. Using that threshold, sensitivity and specificity to detect cataract were 94.4% and 94.7%, respectively.

conclusionWe developed an automatic detection tool for cataract on SS-OCT images. Probability maps of cataract on the images provide an additional tool to help the physician in its diagnosis and surgical planning.

Indexed as

CataractDeep LearningLens, CrystallineHumansROC CurveTomography, Optical CoherenceArtificial intelligenceCataractDeep learningOptical coherence tomogrpahy

Identifiers

PMID36229338
PMCPMC9732477

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.